The effect of multiple doses of rifabutin (150 mg) on the pharmacokinetics of saquinavir-ritonavir (1,000 mg of saquinavir and 100 mg of ritonavir [1,000/100 mg]) twice daily (BID) was assessed in 25 healthy subjects. Rifabutin reduced the area under the plasma drug concentration-time curve from 0 to 12 h postdose (AUC(0-12)), maximum observed concentration of drug in plasma (C(max)), and minim...

Abstract Background The improvement of maize hybrids relies on significant genetic variability among the inbred lines used and degree to which it is transferred progeny. Understanding parameters heritability traits in every population an essential precondition for selection program. This study was designed estimate magnitude line × tester mating design. Fifteen yellow derived from different sou...

BACKGROUND Currently, less frequent than once-weekly subcutaneous epoetin administration regimens were shown to be equally effective and safe as once-weekly schedules in stable predialysis and peritoneal dialysis patients. Bioequivalency of once-every-2-weeks and once-weekly subcutaneous administration of the same total dose of epoetin beta for the maintenance phase of anemia treatment in stabl...

Background & Aims: In regard to the importance of atropine and scopolamine as medicines with natural source, this study was aimed to investigate the effect of chloramphenicol as an inhibitor of protein synthesis on the alkaloids content of Datura stramonium. Method: After initial preparation of medicinal garden seeds, they were planted 50 cm apart in four different sections. Three different con...

Grazing management is a key element determining herbage production and grazing efficiency. This study measured herbage accumulation and grazing efficiency in Mombaça grass pastures (Panicum maximum cv. Mombaça) subjected to intermittent defoliation managements. Treatments were combinations of 2 rest periods (grazing at either 95 or 100% canopy light interception — LI) and 2 grazing intensities ...

an application of aerated concret (foam concrete) was experimentally studied. in this study the compressive strength of the proposed concrete was measured the effect of parameters such as aggregate size of broken stone, quantity of cement and various densities were exprementally studies, and the best mixture was select.these prepared mixtures are practically useful to optimize the consumption o...

A retracting-free bidirectional circuit in a graph G is a closed walk which traverses every edge exactly once in each direction and such that no edge is succeeded by the same edge in the opposite direction. Such a circuit revisits each vertex only in a number of steps. Studying the class Ω of all graphs admitting at least one retracting-free bidirectional circuit was proposed by Ore (1951) and ...

In laboratory tests, larvae of the Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say), and the sugarbeet wireworm (SBW), Limonius californicus (Mannerheim), were exposed to the nematodes Steinernema feltiae Filipjev (Mexican strain) (= Neoaplectana carpocapsae) and S. glaseri Steiner in soil. S. feltiae caused significantly higher mortality in SBW larvae than did S. glaseri, but both...