Hemolysis, oxidative stress, inflammation, vaso-occlusion, and organ infarction are hallmarks of sickle cell disease (SCD). We have previously shown that increases in heme oxygenase-1 (HO-1) activity detoxify heme and inhibit vaso-occlusion in transgenic mouse models of SCD. HO-1 releases Fe(2+) from heme, and the ferritin heavy chain (FHC) ferroxidase oxidizes Fe(2+) to catalytically inactive ...

Brassinosteroids (BRs) are steroid hormones that modulate numerous physiological processes in plants. However, few studies have focused on the involvement of BRs in sensing and responding to the stress of mineral nutrient deficiency. In the present study, we evaluated the roles of BRs in the response of rice (Oryza sativa) to iron (Fe) deficiency during Fe uptake, transport, and translocation. ...

We have investigated the propagation of {332}<113> twins in a multilayered Ti-10Mo-xFe (x = 1-3) alloy fabricated by multi-pass hot rolling. The material contains a macroscopic Fe-graded structure (about 130 μm width) between 1 and 3 wt% Fe in the direction perpendicular to rolling. We observe strong influence of the Fe-graded structure in the twin propagation behavior. The propagation of {332}...

We report a simple, yet general, approach to monodisperse MPt (M = Fe, Co, Ni, Cu, Zn) nanoparticles (NPs) by coreduction of M(acac)2 and Pt(acac)2 (acac = acetylacetonate) with oleylamine at 300 °C. In the current reaction condition, oleylamine serves as the reducing agent, surfactant, and solvent. As an example, we describe in details the synthesis of 9.5 nm CoPt NPs with their compositions c...

Iron oxide nanoparticles (NPs) are commonly utilized for biomedical, industrial, and commercial applications due to their unique properties and potential biocompatibility. However, little is known about how exposure to iron oxide NPs may affect susceptible populations such as pregnant women and developing fetuses. To examine the influence of NP surface-charge and dose on the developmental toxic...

AbstractIn this paper, we investigate effect of Fe–intermetallic compounds on plastic deformation of closed-cell composite Aluminum Foam as filler of thin-walled tubes. However, deformation of the Aluminum foam-filled thin-walled tubes as crushed-box will be presented in Part (II). Composite foams of AlSi7SiC3 and AlSi7SiC3-(Fe) as closed cell were synthesized by powder metallurgy foaming metho...

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

modified cellulose acetate (ca) membranes were prepared by dissolving the polymers in a mixture of acetone (ac) and n, n dimethylacetamide (dmac) (70:30) solvent and deionized (di) water was used in the coagulation bath. the introduction of polyethylene glycol (peg) additive and tio2 nanoparticles (nps) into the casting solution has changed the structures of the resulting membranes during the p...

Although matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) can be employed to rapidly characterize pathogenic bacteria, bacterial cultures are generally required to obtain sufficient quantities of the bacterial cells prior to MALDI MS analysis. If this time-consuming step could be eliminated, the length of time required for identification of bacterial strains would be gre...

Recently, the use of superparamagnetic iron oxide nanoparticles (SPIONS) as a new and promising source of iron in agriculture has been suggested that further investigation is needed before extensive field use. In a greenhouse experiment, the effect of coated magnetite nanoparticles with humic acid (Fe3O4/HA NPs) was investigated on iron deficiency chlorosis and photosynthesis efficiency compare...