There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of morphine dependence. In this study, the effects of acute and chronic administration of nitrendipine on naloxone precipitated morphine withdrawal signs were investigated. Mice were rendered dependent to morphine by subcutaneous injection of morphine over a period of 5 days. In chronic s...

Clinical data showed consumption of buckwheat played a very positive role in the relief of diabetes and its complications. The purpose of this study was to explore the effects and mechanisms of the overall flavonoids from buckwheat flowers and leaves (TFBFL) on renal damage in type 2 diabetes mellitus (T2DM) rats. Seventy male Wistar rats were selected. Ten rats were randomly allocated into a n...

Clinical data showed consumption of buckwheat played a very positive role in the relief of diabetes and its complications. The purpose of this study was to explore the effects and mechanisms of the overall flavonoids from buckwheat flowers and leaves (TFBFL) on renal damage in type 2 diabetes mellitus (T2DM) rats. Seventy male Wistar rats were selected. Ten rats were randomly allocated into a n...

There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of morphine dependence. In this study, the effects of acute and chronic administration of nitrendipine on naloxone precipitated morphine withdrawal signs were investigated. Mice were rendered dependent to morphine by subcutaneous injection of morphine over a period of 5 days. In chronic s...

turnips with a long history of usage, are helpful in preventing breast and prostate cancer, inflammation and body`s immune system dysfunction. in this study, we investigated the effects of chloroform, ethyl acetate and methanolic extracts of brassica rapa l. on cell-mediated immune response in mice. chloroform, ethyl acetate and methanolic extracts of b. rapa glands were prepared by maceration ...

Background: Ondo city in Ondo State Nigeria includes Ondo East and West could be described as a research city due to antecedent number of research institutes. Materials and Methods: Dose due to radioactivity content of soil samples from sixteen waste dump sites in Ondo, Southwestern Nigeria was determined using gamma-ray spectrometer in order to evaluate the radiation hazard health profile and ...

influence of folic acid on the cns is still unclear. folate has a neuroprotective effect, while on the other hand excess folate can exacerbate seizures in epileptics. the aim of the present study was to examine the effect of subchronic administration of folic acid on behavioural and electroencephalographic (eeg) characteristics of dl homocysteine thiolactone induced seizures in adult rats. t...