In an attempt to develop a probiotic formulation for poultry feed, a number of lactic acid bacteria (LAB) were isolated from chicken intestinal specimens and a series of in vitro experiments were performed to evaluate their efficacy as a potential probiotic candidate. A total of 650 LAB strains were isolated and screened for their antagonistic potential against each other. Among all the isolate...

Clostridium difficile is the commonest cause of antibiotic-associated diarrhoea, with the hospitalized elderly being at particular risk. The organism makes a crystalline surface protein layer (S-layer), encoded by the slpA gene, the product of which is cleaved to give two mature peptides which associate to form the layer. The larger peptide (high molecular weight; HMW), derived from the C-termi...

OBJECTIVE To investigate visceral leishmaniasis (VL) deaths and risk factors in two VL endemic areas of Bangladesh. DESIGN Retrospective cross-sectional. SETTING Two geographically and culturally different VL endemic subdistricts, Godagari in the district of Rajshahi and Trishal in the district of Mymensingh in Bangladesh, August 2009-December 2011. PARTICIPANTS 51 094 inhabitants from ra...

INTRODUCTION A subcategory of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) is characterized by accumulation of fat accompanied by inflammatory infiltration and hepatocellular damage. The active complex of milk thistle is a lipophilic extract from its seeds, comprising three isomers, collectively known as silymarin. Silymarin has demonstrated antioxidant, anti-in...

Although several inherited melanoma predisposition syndromes have been identified, a subset of families lack pathogenic variants in known highly penetrant genes, including CDKN2A, CDK4, and BAP1. We describe patient with multiple melanomas other primary tumors germline variant BUB1B. A 76-year-old woman presented history multiple, distinct tumors, childhood thymoma, thyroid cancer, two melanoma...