Background Women with Sjögren’s syndrome (SS) are more likely to experience vaginal dryness, dyspareunia and reduced sexual function than healthy controls 1 . There is limited data investigating relationships psychosocial influences, such as coping mechanisms, illness perceptions, partners behaviours relationship satisfaction. Objectives To investigate associations between parameters in women S...

We report on a detailed experimental study of the electron transport anisotropy in HgTe (013) quantum well 22 nm width directions [100] and [031¯] as density function n. The is absent at minimal near charge neutrality point. increases with increase n reaches about 10% when Fermi level within first subband H1. There sharp (up to 60%) second E2. conclude that effect due small intra-subband anisot...

Screening of twenty five plant extracts for larvicidal activity against Culex quinquefasciatus Say (Diptera: Culicidae) Samuel Tennyson, K John Ravindran, S Arivoli Department of Zoology, Madras Christian College, 600 059, Tamilnadu, India National Institute of Malaria Research (ICMR), Field Unit Chennai, National Institute of Epidemiology Campus, Chennai 600 077, Tamilnadu, India P.G. & Resear...

The structures of two major phosphoglycolipids from the thermophilic bacteria Thermus oshimai NTU-063, Thermus thermophilus NTU-077, Meiothermus ruber NTU-124, and Meiothermus taiwanensis NTU-220 were determined using spectroscopic and chemical analyses to be 2'-O-(1,2-diacyl-sn-glycero-3-phospho) -3'-O-(alpha-N-acetyl-glucosaminyl)-N-glyceroyl alkylamine [PGL1 (1)] and the novel structure 2'-O...

Introduction FMF is a monogenic autoinflammatory disease with recurring episodes of fever and serositis attacks. FMF is associated with mutations in pyrin. On the other hand mutations in a molecule in the same pathway, cryopyrin, is characterized by inflammatory features involving the inner ear as well. A study has suggested the involvement of cochlea in Behçet disease, which is a polygenic aut...

When intact cells (HeLa S-3, mouse 3T3 fibroblasts, hen erythrocytes) are incubated with the rifamycin SV derivative AF/OI3, which is widely used as a potent inhibitor of mammalian DNA-dependent RNA polymerases, a rapid and extensive disintegration of the plasma membrane takes place. This cell disruption results, for example, in hemolysis of the erythrocytes at concentrations above 50 JLg/ml, i...

Heat shock protein 90 (HSP90) inhibitors are potential drugs for cancer therapy. The inhibition of HSP90 on cancer cell growth largely through degrading client proteins, like Akt and p53, therefore, triggering cancer cell apoptosis. Here, we show that the HSP90 inhibitor 17-AAG can induce the expression of GRP75, a member of heat shock protein 70 (HSP70) family, which, in turn, attenuates the a...