background: endometriosis is a common chronic inflammation which leads to infertility and chronic pelvic pain in affected women. secretory phospholipase a2 type iia (spla2iia) is an acute phase reactant that is markedly increased in inflammatory disorders. objective: to assess the effects of ω-3 and ω-6 polyunsaturated fatty acids (pufas) administration in endometrial cells culture on spla2iia ...

Previous studies show that the collagen fibrils of the mammalian vitreous humor are assembled largely from type I1 collagen with smaller amounts of type IX collagen and either type V or type XI collagen. In this paper, we report the separation of two chains of type V/type XI collagen from type I1 collagen by heparinSepharose chromatography. These chains were characterized by sequencing of selec...

Several lines of evidence suggest that host genetic factors controlling the immune response influence infection by Mycobacterium tuberculosis. The proinflammatory cytokine interleukin (IL)-1beta and its antagonist, IL-1Ra (IL-1 receptor agonist), are strongly induced by M. tuberculosis and are encoded by polymorphic genes. The induction of both IL-1Ra mRNA and secreted protein by M. tuberculosi...

In this paper we consider the notion of A2 -statistical convergence for real double sequences which is an extension of the notion of AI -statistical convergence for real single sequences introduced by Savas, Das and Dutta. We primarily apply this new notion to prove a Korovkin type approximation theorem. In the last section, we study the rate of A2 -statistical convergence.

Several antigens have been tested as vaccine candidates against Leishmania infections but controversial results have been reported when different antigens are co-administered in combined vaccination protocols. Immunization with A2 or nucleoside hydrolase (NH) antigens was previously shown to induce Th1 immune responses and protection in BALB/c mice against Leishmania donovani and L. amazonensis...

Fluorescence resonance energy transfer between cyan fluorescent protein- and yellow fluorescent protein-tagged MHC class I molecules reports on their spatial organization during assembly and export from the endoplasmic reticulum (ER). A fraction of MHC class I molecules is clustered in the ER at steady state. Contrary to expectations from biochemical models, this fraction is not bound to the TA...

This article summarizes the development of an analytical method for the determination of proanthocyanidin (PAC) A2 in phenolic polymer isolates following acid-catalyzed degradation in the presence of excess phloroglucinol. Isolates from concentrated cranberry juice (CCJ) were extensively characterized and molar extinction coefficients were determined for the terminal A2 and phloroglucinol adduc...

We have previously described several receptors on the chondrocyte membrane. In an attempt to further characterize the coupling mechanisms of serotoninergic receptors, here we examined the involvement of serotonin in the phospholipase A2 activity. Serotonin dose-dependently stimulated phospholipase A2. This activation enhanced collagenase type II activity and had no effect on proteoglycanase act...