Abstract Cancer invasion and metastasis are influenced by a plethora of biochemical processes involve many mechanisms, among which chemotaxis haptotaxis two the main mechanisms directing migration cancer cells Chaplain Lolas (2005). Evidence has been found that release complex enzymes such as urokinase-type plasminogen activator (uPA), degrade surrounding extracellular matrix (ECM), thereby all...

Gc-globulin has been found in bronchoalveolar lavage fluid in patients with chronic obstructive pulmonary disease (COPD) and adult respiratory distress syndrome (ARDS) and has been shown to enhance neutrophil chemotaxis to C5-derived peptides in vitro. We proposed that Gc-globulin may enhance the inflammatory response in lungs by influencing monocyte chemotaxis to C5-derived peptides as it does...

We study a chemotaxis model describing the space and time evolution in smooth bounded domain of $\mathbb{R}^2$ densities $u$ $v$ subpopulations moving static individuals ...

The nature of the biochemical signal that is involved in the excitation response in bacterial chemotaxis is not known. However, ATP is required for chemotaxis. We have purified all of the proteins involved in signal transduction and show that the product of the cheA gene is rapidly autophosphorylated, while some mutant CheA proteins cannot be phosphorylated. The presence of stoichiometric level...

About half of the human population is infected with Helicobacter pylori, a bacterium causing gastritis, peptic ulcer and progression to gastric cancer. Chemotaxis and flagellar motility are required for colonization and persistence of H. pylori in the gastric mucus layer. It is not completely clear which chemical gradients are used by H. pylori to maintain its position. TlpA, a chemotaxis recep...

We are interested in the effects of diffusivity and chemotaxis on the competition of several species for a limited resource. Diffusivity of cells is also called motility in some engineering literature. Chemotaxis is the oriented movement of cells in response to the concentration gradient of chemical substances in their environment. It is ”anti-diffusion”. It was observed experimentally that mot...

Adaptation has a crucial role in the gradient-sensing mechanism that underlies bacterial chemotaxis. The Escherichia coli chemotaxis pathway uses a single adaptation system involving reversible receptor methylation. In Bacillus subtilis, the chemotaxis pathway seems to use three adaptation systems. One involves reversible receptor methylation, although quite differently than in E. coli. The oth...

The effects of chloramphenicol and p-fluorophenylalanine (p-FPA) on growth, proportion of motile cells, average rate of motility, and the chemotactic response of a methionine auxotroph of Escherichia coli K-12 were studied. Kinetic studies revealed that the inhibition of chemotaxis by p-FPA can be explained by the effect on growth, proportion of motile cells, and average rate of motility rather...