Background: Vitamin D deficiency seems to be associated with pulmonary function deterioration. The present study was designed to investigate the relationship between serum vitamin D and forced expiratory volume in patients with chronic obstructive pulmonary disease (COPD). Methods: From September 2011 to April 2012 eighty consecutive patients with COPD presented to an outpatient clinic of Babo...

Glycogen synthase kinase (GSK)-3β mediates amyloid-beta (Aβ) and oxidative stress-induced neurotoxicity in neurodegenerative disorders. Natural products with antioxidant activity, such as Sargassum (S.) oligocystum may modulate GSK-3β enzyme and protect against Aβ-induced neurotoxicity. Therefore, we aimed to assess the neuroprotective effects of a methanolic extract of S. oligocystum against A...

ABSTRACT We study the significance of running vacuum model in which energy density depends on square Hubble parameter, comparison with ΛCDM model. The Bayesian inference method is employed to appraise relative model, using combined data sets, SN1a+CMB+BAO and SN1a+CMB+BAO+OHD. parameters corresponding errors are estimated from marginal probability function parameters. parameter that distinguish...

Vitamin D deficiency is associated with several adverse health outcomes, and vitamin D appears to have systemic antimicrobial effects that may be crucial in a variety of both acute and chronic illnesses. In the present study, 25-hydroxyvitamin D (25-OHD) levels were compared among patients with chronic hepatitis B virus infection, naturally immunized individuals and control individuals. Thirty-...

BACKGROUND Vitamin D supplementation is widely recommended for infants, but the optimal dose remains unclear. High intake may result in hypercalcemia. METHODS We evaluated the incidence of hypercalcemia during the first year of life in a cohort of 987 healthy children who received 10 or 30 μg of vitamin D3 supplementation daily. Ionized calcium (Ca-ion) was analyzed at 6 and 12 months, and se...

Post-absorption levels of 25-hydroxy vitamin D (25-OHD) after oral administration of 25-hydroxycholecalciferol (25-OHD3) were measured in 11 subjects. Five had presented with steatorrhoea of various causes while six had post-gastrectomy osteomalacia. Post-absorption levels of 25-OHD were low in four of the patients with steatorrhoea but normal in five of those with post-gastrectomy osteomalacia...

BACKGROUND There had been a growing evidence of high prevalence of vitamin D deficiency especially among children which may increase the risk of many chronic diseases in adulthood. AIM Assessment of different lifestyles and dietary behaviour influencing the level of serum 25-OHD in a group of Egyptian prepubescent children. SUBJECTS AND METHODS Two hundred boys and girls aged from 9 to 11 y...

1. Basal levels of serum 25-hydroxy vitamin D (25-OHD) were estimated in ten normal children and twenty-seven children with protein-energy malnutrition. 2. Five normal children and fourteen malnourished children were administered a single massive dose of 15 mg vitamin D orally and the remaining children received oral supplements of 50 micrograms vitamin D daily for 20 d. Blood samples were obta...

OBJECTIVES To compare the performance of 3 commonly used 25-hydroxyvitamin D (25-OHD) assays among a sample of the Saudi population. METHODS This cross-sectional study was carried out between January 2011 and December 2012 at King Fahd Hospital of the University, Al-Khobar, Saudi Arabia. After informed consent, blood samples for measurement of 25-OHD level was extracted from 200 adults. The v...

BACKGROUND vitamin D deficiency is a well-known cause of bone loss and fractures but its association, especially among the oldest old, with muscle weakness is less obvious. OBJECTIVE to investigate the relationship between 25-hydroxyvitamin D (25-OHD) and muscle performance in persons aged 80 years and older. METHODS baseline results of the Belfrail study, a prospective, population-based co...