نتایج جستجو برای: کلاریترومایسین xl
تعداد نتایج: 6878 فیلتر نتایج به سال:
آنتی‌بیوتیک‌ها جزء آلاینده‌های مهم محیط‌های آبی به‌حساب می‌آیند. در این مطالعه حذف آنتی‌بیوتیک کلاریترومایسن از فاضلاب ساختگی از طریق فرایند تلفیقی انعقاد و اکسیداسیون پیشرفته مورد بررسی قرار گرفت. این تحقیق در مقیاس آزمایشگاهی و به‌صورت ناپیوسته انجام شد. فاضلاب ساختگی از آنتی‌بیوتیک کلاریترومایسین با غلظت 200 میلی‌گرم در لیتر ساخته شد. شاخص COD به‌عنوان پارامتر مورد بررسی انتخاب گردید. ابتدا ...
Bcl-xL suppresses mitochondria-mediated apoptosis and is frequently overexpressed in cancer to promote cancer cell survival. Bcl-xL also promotes metastasis. However, it is unclear whether this metastatic function is dependent on its anti-apoptotic activity in the mitochondria. Here we demonstrate that Bcl-xL promotes metastasis independent of its anti-apoptotic activity. We show that apoptosis...
conclusions these results suggest that toxins induce inflammatory responses, particularly through expression of chemokine. recombinant stx and native toxin induced apoptosis by balancing between different pro- and anti-apoptotic bcl-2 family-factors in epithelial cells. in this study, for the first time, recombinant and native stx induction of apoptotic factors and stimulation of immune respons...
PURPOSE To identify determinants of the effect of antisense-mediated Bcl-xl down-regulation (Bcl-xl knockdown) on the response of colorectal cancer cells to SN38, the active metabolite of irinotecan, a topoisomerase I inhibitor licensed for colorectal cancer chemotherapy. EXPERIMENTAL DESIGN Using wild-type HCT116, p53 null, Bax null, or p21/WAF1 null isogenic derivatives, we measured express...
BCL-2 family proteins dictate survival of human multiple myeloma cells, making them attractive drug targets. Indeed, multiple myeloma cells are sensitive to antagonists that selectively target prosurvival proteins such as BCL-2/BCL-XL (ABT-737 and ABT-263/navitoclax) or BCL-2 only (ABT-199/GDC-0199/venetoclax). Resistance to these three drugs is mediated by expression of MCL-1. However, given t...
Cellular and molecular characterization of osteoclasts (OCL) has been extremely difficult since OCL are rare cells, and are difficult to isolate in large numbers. We used the tartrate-resistant acid phosphatase promoter to target the bcl-XL and/or Simian Virus 40 large T antigen (Tag) genes to cells in the OCL lineage in transgenic mice as a means of immortalizing OCL precursors. Immunocytochem...
Extremely large-scale reconfigurable intelligent surface (XL-RIS) has recently been proposed and is recognized as a promising technology that can further enhance the capacity of communication systems compensate for severe path loss. However, pilot overhead beam training in XL-RIS-assisted wireless enormous because near-field channel model needs to be taken into account, number candidate codewor...
Maturation of neuronal synapses is thought to involve mitochondria. Bcl-xL protein inhibits mitochondria-mediated apoptosis but may have other functions in healthy adult neurons in which Bcl-xL is abundant. Here, we report that overexpression of Bcl-xL postsynaptically increases frequency and amplitude of spontaneous miniature synaptic currents in rat hippocampal neurons in culture. Bcl-xL, ove...
Bcl-xL is a member of the Bcl-2 family, playing a critical role in the survival of tumor cells. Here, we show that Bcl-xL oncogenic function can be uncoupled from its anti-apoptotic activity when it is regulated by the post-translational deamidation of its Asn52.Bcl-xL activity can be regulated by post-translational modifications: deamidation of Asn52 and 66 into Asp residues was reported to oc...
We clarify a relation between the XL algorithm and Gröbner bases algorithms. The XL algorithm was proposed to be a more efficient algorithm to solve a system of equations with a special assumption without trying to calculate a whole Gröbner basis. But in our result, it is shown that the XL algorithm is also a Gröbner bases algorithm which can be represented as a redundant version of a Gröbner b...
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