Case report of a patient with rheumatoid arthritis who developed severe neutropenia, splenomegaly and was diagnosed with Felty's syndrome. The patient later developed Kala-azar. Both diseases have similar clinical and laboratory presentation, making the differential diagnosis difficult. The present case report aims at drawing attention to the identification of visceral Leishmaniasis infection i...

Studies with 26 clones of L. donovani promastigotes derived from three different Indian isolates indicated that wild type parasites are mixture of stibanate sensitive and resistant cells. Both forms of the parasite were resistant to the drug. Infection with resistant parasites appears to be the primary reason of high rate of pentavalent antimony unresponsiveness among Indian kala-azar patients....

introduction & objective:visceral leishmaniasis (kala azar), a systemic infectious and life threatening disease of childhood, can be easily diagnosed and treated provided that there is enough knowledge about it otherwise, 90 –95% of patients may die due to severe, acute complications such as bleeding and opportunist infections. following the incubation period and onset of clinical manifestation...

produced in man by inoculation of cultures of Leishmania tropica. Cutaneous inoculation of Leishmania donovani from spleen puncture material from a case of kala-azar, however, is reported to have ' apparently produced kala-azar in a man' but on two occasions accidental inoculation of spleen puncture material from cases of kala-azar was without any effect (Napier, 1927). Recently, Terry et al. (...

‘‘She begged pardon from us, from her child, from Allah...while she was getting down from the bed she closed her eyes, and started moaning. When we held her and made her sit on the bed, she said...Mother, I am dying, I am dying. She collapsed on my lap. We splashed water on her face. We said Doa Durud [religious verse]...then phoned my son.’’ This is how the mother-in-law of the deceased woman ...

Kala-azar is a chronic infection of reticuloendothelial system caused by flagellated protozoan, leishmania donovani injected into human host by the bite of the sand fly (phlebotomous) previously infected by biting and sucking the blood of a patient of leishmaniasis. It is characterized by irregular fever of long duration, large spleen and liver, anaemia, leucopenia and progressive emaciation. T...

couraging results, it was decided to a further extensive trial with this drug in certain hyperendemic kala-azar areas in the tea districts of Mangaldai, as an anti-kala-azar drug of such promising quality was indispensable, especially when, due to present war-time conditions, other pentavalent antimony compounds of proved value, e.g. solustibosan, neostibosan, etc., suitable for mass administra...

We report the case of a six-year-old Brazilian girl referred for splenomegaly who first presented with fever, asthenia, and weight loss. Geographical location, clinical exam, and blood laboratories suggested kala-azar. Serology confirmed kala-azar diagnosis, but direct evidence of the parasites was not made. A treatment by meglumine antimoniate is given under hospital surveillance for two weeks...