نتایج جستجو برای: کارت atm
تعداد نتایج: 15299 فیلتر نتایج به سال:
ATM has a central role in controlling the cellular responses to DNA damage. It and other phosphoinositide 3-kinase-related kinases (PIKKs) have giant helical HEAT repeat domains in their amino-terminal regions. The functions of these domains in PIKKs are not well understood. ATM activation in response to DNA damage appears to be regulated by the Mre11-Rad50-Nbs1 (MRN) complex, although the exac...
x-ATM is a portable toolkit of Asynchronous Transfer Mode (ATM) protocols implemented in a general purpose communications kernel (the x-kernel). The toolkit provides an environment for experimentation with ATM adaptation layers, interoperable ATM signalling, IP over ATM, and real time transport protocols. The x-kernel permits easy composability and promotes protocol modularity, thus x-ATM proto...
The Atm protein kinase is central to the DNA double-strand break response in mammalian cells. After irradiation, dimeric Atm undergoes autophosphorylation at Ser 1981 and dissociates into active monomers. Atm activation is stimulated by expression of the Mre11/Rad50/nibrin complex. Previously, we showed that a C-terminal fragment of nibrin, containing binding sites for both Mre11 and Atm, was s...
BACKGROUND In response to DNA damage, cells undergo either cell-cycle arrest or apoptosis, depending on the extent of damage and the cell's capacity for DNA repair. Cell-cycle arrest induced by double-stranded DNA breaks depends on activation of the ataxia-telangiectasia (ATM) protein kinase, which phosphorylates cell-cycle effectors such as Chk2 and p53 to inhibit cell-cycle progression. ATM i...
The phosphatidyl inositol 3-kinase-like kinases (PIKKs), ataxia-telangiectasia mutated (ATM) and ATM- and Rad3-related (ATR) regulate parallel damage response signalling pathways. ATM is reported to be activated by DNA double-strand breaks (DSBs), whereas ATR is recruited to single-stranded regions of DNA. Although the two pathways were considered to function independently, recent studies have ...
ATM protocols do not implement Hand-off functions that are required to support wireless users. Complementary Signaling solution is proposed to implement handoff functions in an ATM network context to support mobility of wireless users. Complementary Signaling uses switched ATM connections to encapsulate mobility related signaling messages between wireless-to-wire line inter-working nodes at the...
Ataxia telangiectasia patients, with constitutional bi-allelic ATM mutations, have a marked risk of lymphoid tumors and ATM mutation carriers have a smaller risk of cancer. Sporadic ATM mutations occur in 10-20% of chronic lymphocytic leukemia and are often associated with chromosome 11q deletions which cause loss of an ATM allele. The role of constitutional ATM mutations in the pathogenesis of...
Status of this Memo This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Abstract This document specifies an ATM-based protocol for communication between ST2+ agents. The ST2+ over ATM protocol supports the matching of one hop in an ST2+ tree-structure stream with one ATM connection. In this docu...
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