In this paper we will extend the input-to-state stability (ISS) framework introduced by Sontag to continuous-time discontinuous dynamical systems adopting Filippov’s solution concept and using non-smooth ISS Lyapunov functions. The main motivation for investigating non-smooth ISS Lyapunov functions is the recent focus on “multiple Lyapunov functions” for which feasible computational schemes are...

In this paper we will extend the input-to-state stability (ISS) framework introduced by Sontag to continuous-time discontinuous dynamical systems adopting Filippov’s solution concept and using non-smooth ISS Lyapunov functions. The main motivation for investigating non-smooth ISS Lyapunov functions is the recent focus on “multiple Lyapunov functions” for which feasible computational schemes are...

We consider the interconnections of arbitrary topology of a finite number of ISS hybrid systems and study whether the ISS property is maintained for the overall system. We show that if the small gain condition is satisfied, then the whole network is ISS and show how a non-smooth ISS-Lyapunov function can be explicitly constructed in this case. © 2013 Elsevier Ltd. All rights reserved.

Input-to-state stability (ISS) of a feedback interconnection of two discrete-time ISS systems satisfying an appropriate small gain condition is investigated via the Lyapunov method. In particular, an ISS Lyapunov function for the overall system is constructed from the ISS Lyapunov functions of the two subsystems. We consider parameterized families of discrete-time systems that naturally arise w...

Synthetic oligodeoxynucleotides containing CpG motifs [immunostimulatory sequences (ISS)] have been described as potent adjuvants of type 1 immune responses when co-administered with protein or peptide vaccines. To investigate their role in the immune response to polysaccharides (CHO), different preparations of anti-Haemophilus influenzae type b (Hib) conjugate vaccine were administered to mice...

Colibacillosis accounts for significant losses to the poultry industry, and control efforts are hampered by limited understanding of the mechanisms used by avian pathogenic Escherichia coli (APEC) to cause disease. We have found that the presence of the increased serum survival gene (iss) is strongly associated with APEC but not with commensal E. coli, making iss, and the protein it encodes (Is...