OBJECTIVES Testicular germ-cell cancer (TGCC) patients are at risk of developing hypogonadism but no risk factors have yet been defined. METHODS Blood was collected from 143 TGCC patients (after orchidectomy, prior to further therapy (T0) and 6, 12, 24, 36 and 60 months (T6, T12, T24, T36 and T60) after therapy). Biological hypogonadism (BH) was defined as: serum testosterone below 10 nmol/l ...

In this paper we investigated the mechanisms of Baihu Decoction ((白虎汤, BH) and Baihu with Radix Ginseng (BHG) in treating systemic inflammatory response syndrome (SIRS) and sepsis in humans and animals. By reviewing published data on the effects of BH and BHG and the control of blood glucose in treating SIRS and sepsis, we found that (1) BH and BHG were beneficial in the treatment of SIRS and s...

Double neutron star (NS-NS ) binaries, analogous to the well known Hulse–Taylor pulsar PSR 1913+16 (Hulse & Taylor 1975), are guaranteed-to-exist sources of high frequency gravitational radiation detectable by LIGO. There is considerable uncertainty in the estimated rate of coalescence of such systems (Phinney 1991; Narayan et al 1991; Kalogera et al 2001), with conservative estimates of ∼ 1 pe...

Consider the large systems of linear equations A h u h = f h which arise from the discretization of a second-order elliptic boundary value problem. Consider also the preconditioned systems (i) Bh − 1 A h u h = Bh 1 f h; and (ii) A h Bh 1 v h = f h , u h = Bh 1 v h where B h is itself a matrix which arises from the discretization of another elliptic operator. We discuss the effect of boundary co...

Tetrahydrobiopterin (BH(4)) is an essential co-factor for the nitric-oxide (NO) synthases, and in its absence these enzymes produce superoxide (O(2)(·-)) rather than NO. The rate-limiting enzyme for BH(4) production is guanosine triphosphate cyclohydrolase-1 (GTPCH-1). Because endogenously produced NO affects T cell function, we sought to determine whether antigen stimulation affected T cell GT...

NGC6752 hosts in its halo PSR J1911-5958A, a newly discovered binary millisecond pulsar which is the most distant pulsar ever known from the core of a globular cluster. Interestingly, its recycling history seems in conflict with a scenario of ejection resulting from ordinary stellar dynamical encounters. A scattering event off a binary system of two black holes with masses in the range of 3 − 5...

Recently, BH(4)-responsive phenylalanine hydroxylase (PAH) deficiency was reported in patients with specific mutations in the PAH gene, and it was suggested that BH(4) responsiveness may be determined by the respective genotypes. We now report on three patients with PAH deficiency and the same genotype but different responses to standardized BH(4) loading. Our results suggest that BH(4) respons...

Abbreviations: BH: Body Height; HL: Humeral Length; RL: Radial Length; UL: Ulna Length; CL: Clavicle Length; F: Female; M: male; R: Multiple Correlation Coefficient Value; R2: Percentage Contribution by the Explanatory Variable to the Variation in the Dependent Variable (BH); R2adjusted: Compares the Regression Models Containing Different Number of Explanatory Variables (Upper Limbs Segments i....

BACKGROUND Whether bipolar hemiarthroplasty (BH) for displaced femoral neck fractures has benefit over unipolar hemiarthroplasty (UH) remains controversial. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the relative effects between BH and UH. METHODS A systematic literature search (up to April, 2014) was conducted to include RCTs compari...

BACKGROUND Routine clinical use of novel free-breathing, motion-corrected, averaged late-gadolinium-enhancement (moco-LGE) cardiovascular MR may have advantages over conventional breath-held LGE (bh-LGE), especially in vulnerable patients. METHODS AND RESULTS In 390 consecutive patients, we collected bh-LGE and moco-LGE with identical image matrix parameters. In 41 patients, bh-LGE was abando...