نتایج جستجو برای: پروتیین 3a
تعداد نتایج: 13218 فیلتر نتایج به سال:
Iso-butyric acid as a new, simple, and expensive solvent/catalyst was successfully used for the chemoselective Fischer’s synthesis of indolenines derivatives 3a-r by one-pot condensation reaction of various phenylhydrazines 1a-e with the substituted acetophenones 2a-c at reflux conditions. In this protocol, all products 3a-r were obtained in high yields and short reaction time. The structures o...
شوری خاک و آب یکی از عوامل محدودکننده کشت برنج در سراسر دنیا می باشد. این گیاه در مرحله گیاهچه (seedling) حساسیت زیادی نسبت به شوری دارد. پروتئومیکس با توانایی کشف پروتیینها و ژن های پاسخدهنده به تنش، در فرایند اصلاح برای تنش ها به ویژه تنش شوری نقش کاربردی دارد. جهت بررسی اثر تنششوری بر فرآیند های فیزیولوژیکی و الگوی بیان پروتیین های گیاه برنج، بذرهای دو رقم متحمل و حساس، به ترتیب (oryza ...
The phase transitions classes of reaction-diffusion systems with multiparticle reactions are an open challenging problem. Large scale simulations are applied for the 3A --> 4A, 3A --> 2A and the 3A --> 4A, 3A --> [formula : see text] triplet reaction models with site occupation restriction in one dimension. Static and dynamic mean-field scaling are observed with signs of logarithmic corrections...
سابقه و هدف: هیپرگلیسمی که تحت شرایط دیابتیک اتفاق می افتد موجب نقایص متعددی از جمله، نوروپاتی، نفروپاتی و رتینو پاتی می گردد. هنوز اطلاعاتاندکی درباره اثر مستقیم سمیت گلوکز روی سلول های نورونی در دست است.روش بررسی: در این تحقیق ابتدا توان حیاتی سلول ها توسط روشmtt ارزیابی شد و غلظتهای مختلف گلوکز و سپس نقش پروتیین bax در القا آپپتوزسلول های pc12 به عنوان یک مدل آزمایشگاهی از سلول های نورونی مو...
Gallbladder bile of the bullfrog, R a m catesbezana was found to contain a number of minor bile acids and bile alcohols in unconjugated forms. The following bile acids and bile alcohols were identified by combined gas-liquid chromatography-mass spectrometry: cholic acid, allocholic acid, 3a,7a, 12a-trihydroxy-5a-cholestan-26-oic acid, 3a,7a, 12atrihydroxy-24-methyl-5~-cholestan-26-oic acid, 3a,...
Ethanol enhancement of 5-hydroxytryptamine (5-HT)(3A) receptor-mediated responses may have important consequences in the intoxicating and addictive properties of ethanol. Although the exact mechanism is unknown, ethanol-mediated enhancement of 5-HT(3) receptor current has been proposed to occur due to stabilization of the open-channel state. It has not been possible to directly measure the open...
In this study, hMex-3A was selected from TCGA database as a research object to observe the effects of small interfering RNA (siRNA) targeting hMex-3A on the biological activities of human bladder cancer and explore its mechanism for the first time. In this study, there were 2 groups including negative control group and hMex-3A-siRNA-transfected cells group for 5637 and T24 cell lines, respectiv...
The Brn-3a transcription factor stimulates the expression of the anti-apoptotic Bcl-2 and Bcl-x proteins and protects neuronal cells from apoptosis. Here we show that a minimal Bcl-x promoter is activated by Brn-3a and that this stimulation is prevented by the pro-apoptotic p53 protein. Both these effects are mediated via Bcl-x promoter sequences, which are indistinguishable from those required...
RNA-binding proteins (RBPs) play essential roles in RNA metabolism, regulating RNA splicing, transport, surveillance, decay and translation. The aberrant expression of RBPs leads to gene expression alteration and frequently causes various diseases, such as cancer. In this study, we are the first to provide evidence that hMex-3A, a RBP that belongs...
Nanodisks (ND) are ternary complexes of phospholipid, one or more hydrophobic bioactive agents and an apolipoprotein scaffold. These nanoscale assemblies are organized as a disk-shaped lipid bilayer whose perimeter is stabilized by an apolipoprotein scaffold. Solubilization of hydrophobic bioactive agents is achieved by their integration into the ND lipid milieu. When the cis-imidazoline, nutli...
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