OBJECTIVES To assess the time course of phosphorylation of phospholamban residues, the underlying mechanisms determining these phosphorylations, and their functional impact on the mechanical recovery during acidosis. METHODS Langendorff perfused rat hearts were submitted to 30 min of hypercapnic acidosis. Contractility, relaxation, and phosphorylation of phospholamban residues, immunodetected...

The original ν̄μ(or ν̄τ -) energy spectrum from the gravitational collapse of a star has a larger average energy than the spectrum for ν̄e since the opacity of ν̄e exeeds that of ν̄μ(or ντ ). Flavor neutrino conversion, ν̄e ↔ ν̄μ, induced by lepton mixing results in partial permutation of the original ν̄e and ν̄μ spectra. An upper bound on the permutation factor, p ≤ 0.35 (99% CL) is derived using the d...

It is shown that the finite dimensional irreducible representaions of the quantum matrix algebra Mq,p(2) ( the coordinate ring of GLq,p(2)) exist only when both q and p are roots of unity. In this case th e space of states has either the topology of a torus or a cylinder which may be thought of as generalizations of cyclic representations.

It is shown that the finite dimensional ireducible representations of the quantum matrix algebra Mq(3) ( the coordinate ring of GLq(3) ) exist only when q is a root of unity ( q = 1 ). The dimensions of these representations can only be one of the following values: p3 , p 3 2 , p 4 , or p 8 . The topology of the space of states ranges between two extremes , from a 3-dimensional torus S1 × S1 × ...

The inclusive radiative B-decay is a sensitive probe of new physics, especially if related to the virtual exchange of a charged Higgs boson. Supersym-metric models provide a particularly interesting example. In the limit of exact supersymmetry, BR(b → sγ) = 0, due to the vanishing of any magnetic-moment transition operator. We illustrate the impact of this constraint for realistic values of the...

The effect of Ca(2+)/calmodulin-dependent protein kinase II (CaMK II) on voltage-gated ion channels is widely studied through the use of specific CaMK II blockers such as 2-[N-(2-hydroxyethyl)]-N-(4methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine (KN-93). The present study demonstrates that KN-93 is a direct extracellular blocker of a wide range of cloned Kv channels from ...

AMA Saracoglu A, KT, Sorbello M, Çakmak G, Greif R. The influence of the COVID-19 pandemic on videolaryngoscopy: a cross-sectional before-and-after survey. Anaesthesiology Intensive Therapy. 2023;55(2):93-102. doi:10.5114/ait.2023.129278. APA Saracoglu, A., K. T., Sorbello, M., Çakmak, G., & Greif, (2023). Therapy, 55(2), 93-102. https://doi.org/10.5114/ait.2023.129278 Chicago Ayten, Kemal T Ma...