Two novel dicationic binuclear Cu(I) complexes of the type [{(BPPP)E2)}Cu]2[BF4]2 (E = S (3a); Se (3b)) bearing (BPPP)E2 (BPPP bis(diphenyl phosphino)pyridine) pincer systems were isolated, and structurally characterized. The...

We characterized the NADPH-dependent metabolism of 17beta-estradiol (E2) by liver microsomes from 21 male and 12 female human subjects. A large number of radioactive estrogen metabolite peaks were detected following incubations of [3H]E2 with male or female human liver microsomes in the presence of NADPH. The structures of 18 hydroxylated or keto estrogen metabolites formed by these microsomes ...

Background: Electric-quadrupole ($E2$) strengths relate to the underlying quadrupole deformation of a nucleus and present challenge for many nuclear theories. Mirror nuclei in vicinity line $N=Z$ represent convenient laboratory testing deficiencies such models, making use isospin-symmetry systems. Purpose: Uncertainties associated with literature $E2$ \textsuperscript{23}Mg are some largest $T_...

The estrus cycle affects the circadian body temperature (Tb) and activity rhythms, and progesterone is related to these alterations. However, it is not clear whether estrogen (E2) influences it. The present study examined whether E2 affects the circadian Tb and activity rhythm. Ovariectomized rats were implanted with a silastic plate with or without E2 underneath the dorsal skin (E2(-) and E2(+...

The hormone estrogen (E2) binds the estrogen receptor to promote transcription of E2-responsive genes in the breast and other tissues. E2 also has links to genomic instability, and elevated E2 levels are tied to breast cancer. Here, we show that E2 stimulation causes a rapid, global increase in the formation of R-loops, co-transcriptional RNA-DNA products, which in some instances have been link...

Immunological research of steroid-depended chemical carcinogenesis in humans is based on positive experience the clinical usage selective estrogen receptor modulators and experimental design immunological methods for human protection from environmental carcinogens. Our study aimed idiotypic antibodies against benzo[a]pyrene, estradiol progesterone (IgA1-Bp, IgA1-E2 IgA1-Pg), connection with ant...

The branching ratio of the structure dependent (SD) radiative $K^{+} \to e^{+} \nu_{e} \gamma$ decay relative to that $K^+\rightarrow e^+ (\gamma)$ including internal bremsstrahlung (IB) process ($K_{e2(\gamma)}$) has been measured in J-PARC E36 experiment using plastic scintillator/lead sandwich detectors. In analysis, effect IB was also taken into account SD as $K_{e2\gamma(\gamma)}^{\rm SD}$...

El mango cv. Tommy Atkins es cultivado en el departamento del Tolima, principalmente, lugar donde expresa su mejor comportamiento agronómico y calidad de la fruta. objetivo fue evaluar estado nutricional las plantas cuantificar extracción nutrientes por fruta función orden suelo se cultiva. Las concentraciones cada nutriente variaron entre fases muestreadas órgano (hojas, flor fruto) (Entisol e...

Ubiquitin (Ub) signaling requires the covalent passage of Ub among E1, E2, and E3 enzymes. The choice E2 enzymes combined with multiple rounds cascade leads to formation polyubiquitin chains linked through any one seven lysines on Ub. linkage type length act as a signal trigger important cellular processes such protein degradation or DNA damage response. Recently, proteomics studies have identi...

Estradiol (E2) circulates in the blood in three states: unbound (U-E2), bound to sex-hormone binding globulin (SHBG-E2), and bound to albumin. There is evidence to support the concept that only U-E2 and albumin-bound E2, are bioavailable (i.e., rapidly extracted by tissues). A case-control study nested within a large cohort of women, in which we are examining the effect of estrogens on breast c...