Pyranose 2-oxidase (POX) was recovered from Phanerochaete chrysosporium BKM-F-1767 solid substrate culture using mild extraction conditions and was purified. (13)C-nuclear magnetic resonance confirmed production of d-arabino-hexos-2-ulose (glucosone) from d-glucose with the oxidase. Peptide fingerprints generated by liquid chromatography-tandem mass spectrometry of tryptic digests and analysis ...

Poly(ethylene glycol) (PEG)-glycosaminoglycan (GAG) hydrogel networks are established as very versatile biomaterials. Herein, the synthetic gel component of biohybrid materials is systematically varied by combining different poly(2-alkyl-2-oxazolines) (POx) with heparin applying a Michael-type addition crosslinking scheme: POx gradated hydrophilicity and temperature-responsiveness provides poly...

All three sources are limited, the first as to scope of diseases, the second as to time, and the third as to age coverage and degree of completeness in reporting (especially during the war years, 1939-45, which have been ignored). Mortality is referred to where the figures are of interest. The diseases studied are dealt with in the following order: chicken-pox, diphtheria, german measles (rubel...

Sheep pox and enterotoxemia are important diseases of sheep, and these diseases cause severe economic losses to sheep farmers. The present study was undertaken to evaluate the potential of formaldehyde-inactivated recombinant epsilon toxin as a vaccine candidate. The potency of the recombinant epsilon toxoid with aluminum hydroxide as an adjuvant in sheep was determined. Vaccinated sheep were p...

terised in this and in other countries by a striking decrease of small-pox mortality. It must be borne in mind that at the time of the introduction of vaccination a large proportion of the population was protected by previous attacks of small-pox, either natural or inoculated, and that the amount of vaccination adequate to afford a great protection in the earlier years of the century ceased to ...