The influence of secondary hyperparathyroidism (2 HPT) on the set point of the parathyroid hormone (PTH)-Ca(2+) curve is controversial. In vitro experiments have shown an increase in the set point. However, clinical studies with hemodialysis patients have provided a variety of results (increases, decreases and no changes in the set point have been reported). The present study was designed to in...

BACKGROUND Perchlorate (ClO4(-)) is an environmental contaminant known to disrupt the thyroid axis of many terrestrial and aquatic species. ClO4(-) competitively inhibits iodide uptake into the thyroid at the sodium/iodide symporter and disrupts hypothalamic-pituitary-thyroid (HPT) axis homeostasis in rodents. OBJECTIVE We evaluated the proposed mode of action for ClO4(-)-induced rat HPT axis...

X-linked hypophosphatemic rickets (XLH) is a dominant disorder characterized by hypophosphatemia due to impaired renal tubular reabsorption of inorganic phosphate. Cardinal manifestations include defective calcification of cartilage and bone, growth retardation and resistance to phosphorus and vitamin D therapy. Although secondary hyperparathyroidism (HPT) is a common complication of treatment,...

The hyperbolic Pascal triangle HPT 4,q (q ≥ 5) is a new mathematical construction, which is a geometrical generalization of Pascal’s arithmetical triangle. In the present study we show that a natural pattern of rows of HPT 4,5 is almost the same as the sequence consisting of every second term of the well-known Fibonacci words. Further, we give a generalization of the Fibonacci words using the h...

Background: The field of parathyroidectomy (PTx) is complex and brings together many specialists. Even if the surgical approaches changed from classical to minimally invasive PTx, a good outcome is correlated with an adequate localization before and during PTx, while blood assays, such as parathormone (PTH) or 25-hydroxyvitamin D, become useful additional markers. Aim. Specific aspects related ...

The authors previously used the accumulative high-pressure torsion (ACC HPT) method for first time on steel 316, β-Ti alloy, and bulk metallic glass vit105. On low-alloyed alloys, in particular, zirconium alloy Zr-1%Nb, new was not used. This has a tendency to α → ω phase transformations at using simple HPT. When ACC HPT, transformation can be influenced greater extent. article studies sliding ...

It is important for mass storage system to distribute access requests dynamically and balanced between several metadata servers (MDS). Based on analyzing the features of metadata management in the mass storage system, this paper designs the structure of metadata management module, proposes the hash postfix table(HPT) based metadata management algorithm, uses HPT to adjust the distribution of ac...

BACKGROUND Primary hyperparathyroidism (HPT) is one of the most common endocrine disorders, defined by hypersecretion of parathormone. Primary HPT can be caused by adenoma, hyperplasia, and carcinoma. A great amount of mechanisms contribute to the pathogenesis of this disease, such as genetic predispositions because of the germline-inactivating mutations in the multiple endocrine neoplasia type...

BACKGROUND Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is a rare autosomal dominant multiple tumor syndrome characterized by hyperparathyroidism due to single or multiple-gland parathyroid tumor(s). Since it was first described in 1990, the genetics underlying the syndrome have been elucidated and typical clinical presentations are becoming clarified as literature describing this rare entit...

Parathyroid glands produce parathyroid hormone (PTH). PTH has a main role in bone formation. Hyperparathyroidism (HPT) is explained as primary, secondary and tertiary types defined as overproduction of PTH. The brown tumor or osteitis fibrosa cystica is a benign bone lesion that is caused by HPT. This complication has been decreased by diagnosis and successful treatment of secondary hyperparath...