Avascular necrosis of bone is a well-recognised phenomenon in patients on long-term steroid therapy, especially after renal transplantation. There are only four cases reported in the literature of multifocal avascular necrosis after short-term high-dose steroid therapy, and three additional cases are reported in this paper. All the hips have needed reconstructive surgery within two and a half y...

BACKGROUND Persistent pain after total knee arthroplasty (TKA) is dissatisfying to the patient and frustrating to the surgeon. The purpose of this study is to evaluate the aseptic causes and clinical course of intractable pain following TKA. METHODS Of the total 2,534 cases of primary TKA reviewed, 178 cases were classified as having aseptic persistent pain that was not resolved within 1 year...

BACKGROUND Late-onset chronic (low-grade) periprosthetic joint infections are often accompanied by unspecific symptoms, false-negative cultures or nonspecific low values of serum biomarkers. This may lead to the unintended implantation of a revision prosthesis into an infected surgical site with the risk of short-term failure developing again. Conversely, false diagnosis of joint infection may ...

Arthroscopic treatment of chondral lesions of the hip is challenging. Understanding the etiology is paramount not only in treating hip chondral damage but also in mitigating the cause, using arthroscopic means. This article addresses chondral lesions of the hip caused by either injury or morphologic conflicts such as seen in femoroacetabular impingement. Fractures, aseptic necrosis, and metabol...

Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or cort...

Aseptic loosening of total joint arthroplastics due to periprosthetic osteolysis is a frequent cause of implant failure. The absence of clinical interventions to arrest or prevent this complication limits the use of total joint replacement especially in younger patients. Here we review recent studies implicating tumor necrosis factor (TNF)-alpha in periprosthetic osteolysis and the rationale fo...

Anterior cruciate ligament (ACL) ruptures are one of the most common injuries of the knee joint. These injuries occur mostly during contact sporting activities (such as ice hockey or football). Whatever the case, the elective therapy is to reconstruct the ACL by means of implanting a graft. During our experiments we wanted to study the integration of the patellar tendon, which we implanted in t...