نتایج جستجو برای: نمره edss
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INTRODUCTION. In multiple sclerosis (MS), patient disability is assessed according to the qualitative, ordinal Expanded Disability Status Scale (EDSS). In order to monitor treatment efficacy and disease progression, quantitative MRI metrics are sought that will correlate with EDSS [1]. In the relapsing-remitting MS (RRMS) literature, r-values for correlation with EDSS of various metrics have ra...
زمینه: ناتوانی و افسردگی از مهمترین عوامل تعیین کننده کاهش کیفیت زندگی مبتلایان به مولتیپل اسکلروزیس ( ms ) هستند. هدف: مطالعه به منظور تعیین اثر ناتوانی و افسردگی بر کیفیت زندگی مبتلایان به ms انجام شد. مواد و روشها: این مطالعه مقایسهای در سال 1387در شهر قزوین بر روی 53 فرد مبتلا به ms و 53 فرد سالم انجام شد که از لحاظ سن و جنس همتا شده بودند. این افراد با استفاده از مقیاسهای کیفیت ز...
AIM An exploratory study of the relationship between cumulative exposure to subcutaneous (sc) interferon (IFN) β-1a treatment and other possible prognostic factors with long-term clinical outcomes in relapsing-remitting multiple sclerosis (RRMS). METHODS Patients in the original PRISMS study were invited to a single follow-up visit 15 years after initial randomisation (PRISMS-15). Outcomes ov...
OBJECTIVES Data on pregnancy long-term effects on multiple sclerosis (MS) course are still controversial; whether experiencing more than one pregnancy exposes one to risk of the disability's accrual is still unknown. We investigated differences existing in terms of disability progression among women with MS (wwMS) who had one or more children after their MS onset. METHODS Monoparous and multi...
BACKGROUND Magnetic resonance imaging (MRI) is the best biomarker of inflammatory disease activity in relapsing remitting Multiple Sclerosis (RRMS) so far but the association with disability is weak. Appearance of new MRI-lesions is used to evaluate response to immunotherapies in individual patients as well as being the most common primary outcome in phase-2 trials. Measurements of brain atroph...
Daily operation and maintenance tasks are needed to guarantee the correct performance of constructed wetlands. The definition of these activities is a complex task since these actions vary according to the characteristics of each facility. To support the definition of these operation and maintenance protocols an Environmental Decision Support System (EDSS) has been constructed (EDSS-maintenance...
Optical coherence tomography (OCT) is an emerging clinical and research measure of retinal nerve fiber layer (RNFL) loss in multiple sclerosis (MS) and may reflect neurodegeneration. Few studies capture the effect of disease duration on the RNFL in subjects without exposure to disease-modulating therapies.We assessed the relationship of RNFL loss with disease duration in subjects with untreated...
The proposed paper describes the architecture of a GIS-based Environmental Decision Support System (EDSS) that integrates software tools and sensors, such as: remote sensing for environmental monitoring and support to mathematical models, optimization models (for planning plant size, kind, and biomass harvesting), dynamic forest growth models, and models for carbon dioxide balance calculation. ...
• As described in more detail in Ruutiainen et al. (2015), 553 Finnish persons with MS (PwMS) drawn from the membership register of the national patient society completed a postal survey, which aimed at determining the economic and health-related quality of life (HRQoL) burden of MS in Finland. • Survey questionnaire included self-administered EDSS and MSIS-29. EDSS score ranges from 0 to 9 and...
Probing the cortic ospinal tract integrity by transcranial magnetic stimulation (TMS) could help to understand neurophysiological correlations of multiple sclerosis (MS) symptoms. Therefore, study objective was, first, investigate TMS measures (resting motor threshold-RMT, evoked potential (MEP) latency, and amplitude) corticospinal in people with relapsing-remitting MS (pwMS). Then, examined c...
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