OBJECTIVE The prognostic value of inflammation indexes in esophageal cancer was not established. In this study, therefore, both prognostic values of Glasgow prognostic score (GPS) and combination of platelet count and neutrophil lymphocyte ratio (COP-NLR) in patients with esophageal squamous cell carcinoma (ESCC) were investigated and compared. METHODS This retrospective study included 375 pa...

Cop 1 is a synthetic basic random copolymer of L-alanine, L-glutamic acid, L-lysine, and L-tyrosine in a residue molar ratio of 6.0:1.9:4.7:1.0 and with a molecular weight of 21,000 which proved to be effective in specific suppression of experimental allergic encephalomyelitis and has been proposed as a candidate drug against multiple sclerosis. In the present study we further investigated the ...

The original Internet architecture offered a clean contract to endpoints: packets sent will be delivered unmodified 1 or dropped when there is congestion. The proliferation of middleboxes has broken this simple contract to the point where the service the Internet provides to endpoints is entirely unpredictable: • Reachability depends on fields in the packet header and even the payload, as firew...

Communities of Practice (CoP) have long been considered powerful Knowledge Management (KM) mechanisms. CoP, however, are often viewed independently from organizational goals and structures, as they are primarily seen as a means of individual knowledge sharing and learning. In this paper, we argue that CoP supported by social media have great potential to contribute to organizational goals, such...

A relational characterization of cop-win graphs was provided by Nowakowski and Winkler in their seminal paper on the game of Cops and Robbers. As a by-product of that characterization, each cop-win graph is assigned a unique ordinal, which we refer to as a CRordinal. For finite graphs, CR-ordinals correspond to the length of the game assuming optimal play, with the cop beginning the game in a l...

The problem is to determine the number of ‘cops’ needed to capture a ‘robber’ where the game is played with perfect information, the different sides moving alternately. The cops capture the robber when one of them occupies the same vertex as the robber at any time in the game. A copwin graph is one in which one cop can always capture the robber. A graph is cop-win edge-critical with respect to ...

Coatomer is a cytosolic protein complex that forms the coat of COP I-coated transport vesicles. In our attempt to analyze the physical and functional interactions between its seven subunits (coat proteins, [COPs] alpha-zeta), we engaged in a program to clone and characterize the individual coatomer subunits. We have now cloned, sequenced, and overexpressed bovine alpha-COP, the 135-kD subunit o...

SUMMARY OF BACKGROUND DATA The analysis of centre of pressure (COP) excursions is used as an index of postural stability in standing. Conflicting data have been reported over the past 20 years regarding the reliability of COP measures and no standard procedure for COP measure use in study design has been established. SEARCH METHODS Six online databases (January 1980 to February 2009) were sys...

Cryptogenic organizing pneumonia (COP) is a rare pulmonary disorder of unknown etiology. COP with hemoptysis as the primary presenting symptom has rarely been reported. The present study reported a case of COP that resembled lung carcinoma with hemoptysis as the only clinical symptom. The patient recovered well following thoracoscope surgery. A literature review of 119 COP cases between 1995 an...

Dsl1p is required for Golgi-endoplasmic reticulum (ER) retrograde transport in yeast. It interacts with the ER resident protein Tip20p and with delta-COP, a subunit of coatomer, the coat complex of COPI vesicles. To test the significance of these interactions, we mapped the different binding sites and created mutant versions of Dsl1p and delta-COP, which are unable to bind directly to each othe...