Teknolojik ilerlemeyle birlikte her konuda oldu?u gibi haritac?l?kta da bilgiye ula?ma konusunda büyük bir a?ama kaydedildi. ?nsans?z hava araçlar? ile çok say?da h?zl? ?ekilde ula??lan bu dönemde, bilgilerin kullan?l?p anlaml? verilere dönü?türülmesi ayn? ilerleme gerçekle?medi. Operatörler yard?m?yla dönü?türülen veri toplamada i?lenme ihtiyac? do?mu? oldu. Bu çal??mas?nda, arazi hakk?nda bil...

In recent years, knowledge-based systems have become one of the most popular approaches for solving engineering problems. Along with the rising complexity of the problem, knowledge management, acquisition, representation, inferencing, and refinement become increasingly difficult. Conventionally, tasks of knowledge acquisition and representation are accomplished separately and sequentially. Know...

Although Netos are considered auxiliary subunits critical for kainate receptor (KAR) function, direct evidence for their regulation of native KARs is limited. Because Neto KAR regulation is GluK subunit/Neto isoform specific, such regulation must be determined in cell-type-specific contexts. We demonstrate Neto1/2 expression in somatostatin (SOM)-, cholecystokinin/cannabinoid receptor 1 (CCK/CB...

INTRODUCTION The aim of this study was to evaluate the efficacy of Hypericum perforatum for prevention of adhesion formation in rats. MATERIAL AND METHODS Twenty-four female wistar rats underwent left uterine horn adhesion model. Rats were randomised into 4 groups. Group 1 (Control): Closure of abdominal incision without any agent administration. Group 2: Closure of incision after administrat...

Hypericum perforatum L. is an important medicinal plant for the treatment of depression. The plant contains bioactive hypericins that accumulate in dark glands present especially in reproductive parts of the plant. In this study, pathogenesis-related class 10 (PR-10) family genes were identified in H. perforatum, including three previously unidentified members with sequence homology to hyp-1, a...

As the call for this workshop stated: "Place has become a hot topic in GIScience". But what is place, and what are the implications of developing place-based methods? In my talk, I set out an agenda for place-based methods, and particularly for retrieval based on place. In doing so, I explore how unstructured text and tagged images can, firstly, inform methods which seek to take account of noti...

In the present study, the feeding stage, body parts, development and sex specific activity of Glutathione S-transferases (GSTs) were observed in different mosquito species (Aedes aegypti, Culex quinquefasciatus, Anopheles stephensi, An. culicifacies, An. annularis, An. subpictus, An. vagus). GST activity was assayed spectrophotometrically at 23°C, using a UV Max microplate Reader, to measure th...

We identified four PDZ domain-containing proteins, syntenin, PICK1, GRIP, and PSD95, as interactors with the kainate receptor (KAR) subunits GluR5(2b,) GluR5(2c), and GluR6. Of these, we show that both GRIP and PICK1 interactions are required to maintain KAR-mediated synaptic function at mossy fiber-CA3 synapses. In addition, PKC alpha can phosphorylate ct-GluR5(2b) at residues S880 and S886, a...

Different kainate receptor (KAR) subtypes contribute to the regulation of both excitatory and inhibitory transmission. However, no study has reported a role for KAR subtypes in behavioral responses to persistent pain and fear memory. Here we show that responses to capsaicin or inflammatory pain were significantly reduced in mice lacking glutamate receptor 5 (GluR5) but not GluR6 subunits. In cl...