BACKGROUND The IOM report, Preventing Medication Errors, emphasizes the overall lack of knowledge of the incidence of adverse drug events (ADE). Operating rooms, emergency departments and intensive care units are known to have a higher incidence of ADE. Labor and delivery (L&D) is an emergency care unit that could have an increased risk of ADE, where reported rates remain low and under-reportin...

OBJECTIVES To determine the association between inappropriate medication use and self-reported adverse drug effects (ADEs). DESIGN Prospective cohort study with three annual mailed surveys. SETTING Population-based sample of Iowa Medicare beneficiaries. PARTICIPANTS Cohort members (n5626) with established mobility disability and complete pharmacy dispensing records, continuous Medicare el...

Overview of Medication Errors and Adverse Drug Events Medication errors (MEs) are the most common type of medical error occurring in the intensive care unit (ICU). The definitions and incidence rates for MEs and types of adverse drug events (ADEs) are listed in Table 1-1. Medication errors may result in patient injury, but this is not a requirement to be considered an error. Clinicians strive t...

We try to determine the partition function of N = 4 ADE gauge theory on K3 by self-dualizing our previous ADE partition function. The resulting partition function satisfies gap condition.

OBJECTIVE Performance of computerized adverse drug event (ADE) monitoring of electronic health records through a prospective ADE Monitor and ICD9-coded clinical text review operating independently and simultaneously on the same patient population for a 10-year period are compared. Requirements are compiled for clinical decision support in pharmacy systems to enhance ADE detection. METHODS A l...

The follicular cells surrounding Xenopus oocyte under voltage clamp produce K(+)-current responses to follicle-stimulating hormone (FSH), adenosine (Ade), and intracellularly applied cAMP. We previously reported that these responses are suppressed by the stimulation of P2Y receptor through phosphorylation by PKC presumably of the ATP-sensitive K(+) (K(ATP)) channel. This channel comprises sulfo...

BACKGROUND Angiogenesis is crucial for wound healing and exogenous supplements of the angiogenic growth factors have been known to promote cutaneous wound healing. Angiopoietin (Ang) 1 is a recently discovered angiogenic factor and there have been few studies of its effect on cutaneous wound healing. OBJECTIVE We examined the effect of Ang 1 on cutaneous wound healing. METHODS Cartilage oli...

The oxidation of atmospheric CH4 in upland soils is mostly mediated by uncultivated groups of microorganisms that have been identified solely by molecular markers, such as the sequence of the pmoA gene encoding the β-subunit of the particulate methane monooxygenase enzyme. The objective of this work was to compare the activity and diversity of methanotrophs in Amazonian Dark Earth soil (ADE, Ho...

Intracoronary continuous thermodilution is a novel technique to quantify absolute coronary flow (Q) and resistance (R) has potential advantages over current methods such as reserve (CFR) index of microvascular (IMR). However, no data are available in patients with ischemia nonobstructive artery disease (INOCA). This study aimed assess the relationship Q R established CFR/IMR INOCA patients, exp...

Adverse drug events (ADEs) are responsible for unnecessary patient deaths making them a major public health issue. Literature estimates 1% of ADEs recorded in Electronic Health Records (EHRs) are reported to federal databases making EHRs a vital source of ADE-related information. Using Columbia University Medical Center (CUMC)'s EHRs, we developed an algorithm to mine for vaccine-related ADEs o...