derived from the heptad repeat 2 (HR2) region of HIV1 glycoprotein 41 (gp41). The inhibitor binds to the gp41 heptad repeat 1 (HR1) region, thereby blocking viral HR1/HR2 association. Mutations in HR1 have been reported to cause enfuvirtide resistance and reduce viral fitness. In this study, we first showed that scores obtained by a residue-specific all-atom probability discriminatory function ...

Three kinds of inorganic alkali are introduced into tetraethylenepentamine (TEPA)and polyethyleneimine (PEI)-modified MCM-41 as the CO2 adsorbents. FT-IR and TGA are used to characterize the surface groups and the thermal stability of adsorbents. Chemical titration method is used to measure the alkali amounts of adsorbents. Thermo-gravimetric analysis with 10% CO2/90% N2 as the simulated flue g...

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Xiao, Zhi-Qiang, and Adhip P. N. Majumdar. Induction of transcriptional activity of AP-1 and NF-kB in the gastric mucosa during aging. Am J Physiol Gastrointest Liver Physiol 278: G855–G865, 2000.—Although aging enhances expression and tyrosine kinase activity of epidermal growth factor receptor (EGFR) in the gastric mucosa, there is no information about EGFR signaling cascades. We examined the...

Sarna, Sushil K., Asensio Gonzalez, and Robert P. Ryan. Enteric locus of action of prokinetics: ABT-229, motilin, and erythromycin. Am J Physiol Gastrointest Liver Physiol 278: G744–G752, 2000.—We investigated the in vivo and in vitro locus of actions of prokinetics: motilin, erythromycin, and ABT-229. The test substances were infused close intra-arterially in short segments of the jejunum in t...