Multipath routing is a technique that allows tra c dispersion and so, through the use of load-balancing, nodes energy consumption minimization or analysis for tra c prevention, it is capable to improve performance in mobile ad hoc networks. In this work we compare multipath version for two reactive protocols: DYMO and DSR. We study the impact of tra c dispersion on both UDP and TCP tra c. Moreo...

Recently the notion of self similarity has been shown to apply to wide area and local area network tra c In this paper we examine the mechanisms that give rise to the self similarity of network tra c We present a hypothesized explanation for the possible self similarity of tra c by using a particular sub set of wide area tra c tra c due to the World Wide Web WWW Using an extensive set of traces...

In Caenorhabditis elegans, the tra-2 sex-determining gene is regulated at the translational level by two 28 nt direct repeat elements (DREs) located in its 3' untranslated region (3'UTR). DRF is a factor that binds the DREs and may be a trans-acting translational regulator of tra-2. Here we identify two genes that are required for the normal pattern of translational control. A newly identified ...

Markov modulated models are often used to model tra c in a network. How well the processes really capture the essentials of real tra c is less known. We review some of these models and apply a number of associated tting methods to an Ethernet tra c in di erent timescales. The tted models are then used as input to a bu er where bu er occupancies are used as a measure of the goodness of the model...

This paper describes an experimental study of constraint-based network design. We used a novel network design tool, implemented in Java, to design representative networks joining major U.S. cities. The cost of three topologies: Best Star, Minimum Spanning Tree (MST), and Delaunay Triangulation, are compared, with and without localized tra c constraints. The best star network gives near optimal ...

Pancreatic cancer is highly malignant with limited therapy and a poor prognosis. TRAIL-activating therapy has been promising, however, clinical trials have shown resistance and limited responses of pancreatic cancers. We investigated the effects of calmodulin(CaM) antagonists, trifluoperazine(TFP) and tamoxifen(TMX), on TRA-8-induced apoptosis and tumorigenesis of TRA-8-resistant pancreatic can...

Transradial arterial access (TRA) has been employed for transcatheter coronary procedures for more than 25 years, with numerous studies demonstrating improved patient safety as compared with transfemoral arterial access. However, TRA remains underused by the interventional radiology and vascular surgery communities. Advantages of TRA over transfemoral arterial access include easier accomplishme...

To date, a range of exercises have been used to improve the function of the lumbar multifidus (LM) and transversus abdominis (TrA) muscles in people with low back pain, but uncertainty remains as to what exactly constitutes meaningful LM and TrA training. We examined the effects of exercising with a new device which combines weight-bearing, an unstable base of support (BOS) (feet), an upright p...

We propose a simple and robust automatic strategy for managing SDH/SONET and/or ATM virtual paths in real time to handle slow tra c variations. It consists of on-line measurements of o ered tra cs followed by the design and possible implementation of a new virtual path network in a repeated cycle. Methods and parameters for tra c measurements and network updating are studied and optimised to ac...

PCN188 SubCutaNeouS VS INtraVeNouS admINIStratIoN of traStuzumab IN Her2+ breaSt CaNCer PatIeNtS: a maCedoNIaN CoSt-mINImIzatIoN aNalySIS Nestorovska A1, Naumoska Z1, Grozdanova A1, Stoleski D2, Ivanovska A2, Risteski M3, Vasev N3, Ismaili I3, Stefanovski P4, Dimovski A1, Suturkova L1, Sterjev Z5 1ISPOR Republic of Macedonia regional chapter, Skopje, Macedonia, 2Roche Macedonia, DOOEL, Skopje, ...