نتایج جستجو برای: مادۀ 143 قمم
تعداد نتایج: 13272 فیلتر نتایج به سال:
در بیشتر نظام‌های حقوقی در قراردادهای الکترونیکی، برای مصرف‌کننده حق انصراف از عقد پیش‌بینی شده است. مادۀ 37 قانون تجارت الکترونیکی ایران نیز با الهام گرفتن از مادۀ 6 دستورالعمل مصوب 1997م اتحادیۀ اروپا، از حق انصراف مصرف‌کننده برای حداقل هفت روز کاری سخن گفته است. برخی نویسندگان این حق را یک خیار نوین قانونی و برخی دیگر آن را نوعی حق ابطال عقد شمرده‌اند. مقایسۀ مادۀ 37 و مادۀ 6 دستورالعمل یادش...
MicroRNAs (miRNAs) play an essential role in the onset and development of many cardiovascular diseases. Increasing evidence shows that miRNAs can be used as potential diagnostic biomarkers for cardiovascular diseases, and miRNA-based therapy may be a promising therapy for the treatment of cardiovascular diseases. The microRNA-143/-145 (miR-143/-145) cluster is essential for differentiation of v...
Endometrial cancer (EC) is one of the most commonly diagnosed gynecologic malignancies in the world, with the morbidity rate of over 7%. The mechanism of the pathogenesis has not been specifically elucidated to date, which is imperative for EC treatment. The aim of our study was to investigate the target relationship between miR-143 and mitogen-activated protein kinase 1 (MAPK1) and explore the...
MicroRNAs (miRNAs), 18-24 nt non-coding RNAs, are thought to play important roles in cell proliferation, differentiation, apoptosis, and development. Recent studies suggest that some of the known microRNAs map to a single genomic locale within a single polycistronic transcript. But the roles of the cluster remain to be known. In order to understand the role and mechanism of a cluster of miR-143...
Smooth muscle cells (SMCs) retain remarkable plasticity to undergo phenotypic modulation in which the expression of smooth muscle markers is markedly attenuated while conversely expression of extracellular matrix (ECM) is dramatically up-regulated. Myocardin is perhaps the most potent transcription factor for stimulating expression of smooth muscle-specific genes; little is known, however, abou...
Insulin-like growth factor 1 receptor (IGF1R) is a transmembrane receptor that is activated by insulin-like growth factor 1 (IGF-1) and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors and plays an important role in colorectal cancer etiology and progression. In this study, we used bioinformatic analyses to search for miRNAs that potentially target I...
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