Glioma is the most common primary tumor of central nervous system. We previously confirmed that zinc finger E-box binding homeobox (ZEB) 2 promotes malignant progression glioma, while microRNA-637 (miR-637) associated with favorable prognosis in glioma. This study aimed to investigate potential interaction between ZEB2 and miR-637 its downstream signaling pathway The results revealed could dire...

The neuroprotective role of propofol in transient global and focal cerebral ischemia reperfusion (I/R) animal model has recently been highlighted. However, no studies have conducted to explore the relationship between mitochondrial fission/fusion and I/R injury under the intervention of propofol. Moreover, neuroprotective mechanism of propofol is yet unclear. Culturing primary hippocampal cells...

The N-methyl-D-aspartate receptor is an important mediator of the behavioral effects of ethanol in the central nervous system. Previous studies have demonstrated sites in the third and fourth membrane-associated (M) domains of the N-methyl-D-aspartate receptor NR2A subunit that influence alcohol sensitivity and ion channel gating. We investigated whether two of these sites, Phe-637 in M3 and Me...

OBJECTIVE The objective of this work was to evaluate the importance of the degree of light polarization in stimulation of cellular metabolism. BACKGROUND DATA Although the possible role of polarization's effects on the mechanisms of laser phototherapy is sometimes discussed in the literature, there are still no clear answers. MATERIAL AND METHODS A model system (HeLa cell suspension) was us...

Abstract Background and aims Relative Bradycardia (RB) is a poorly understood condition that refers to inappropriately low heart rate response given increase in body temperature. Dysfunctional crosstalk between the immune system autonomous nervous has been advocated. It most often observed intracellular gram negative parasitic infections, with prevalence ranging 15% 20%. The aim of this study w...

Abstract Aim A systematic, qualitative review of the literature available on choroid plexus tumours (CPTs) in paediatric population, published within last 5 years. Method Medline and Embase databases were used to identify suitable papers, 70 papers eligible for inclusion. Inclusion criteria: (1) Paediatric (2) Choroid lesions any grade, (3) Human subjects, (4) available, (5) Author name (6) Eng...

شرایط اکولوژیک مثل دسترسی به غذای کافی و مناسب از عواملی است که می‌تواند روی رفتار جانوران تاثیرگذار باشد. حشرات مختلفی در زمان گرسنگی سعی می‌کنند تا رفتارهای آمیزشی طول مدت آمیزش را کاهش دهند. هدف این مطالعه، بررسی اثر بر عملکرد کفشدوزک Hippodamia variegata بود. آزمایش، نرها ماده‌های ۱۰ ۱۵ روزه باکره استفاده شد. هر تکرار، یک نر ماده ۳ ساعت (از ۱۲ الی ۱۵) برای کنار هم قرار داده شدند ‌زمان تاخیر...

نوآوری در نتیجه ترکیبی از عناصر دانش سازمان‌ها ظاهر شده و به‌عنوان ماده خام اصلی برای نظر گرفته می‌شود. روش‌های سنتی دیگر اثربخش نیست به رویکردهای جدید همچو نیاز است. هدف پژوهش حاضر ، بررسی تأثیر قابلیت‌های مدیریت بر عملکرد با اثر میانجی باز است که 25 واحد‌ فناور مستقر «پارک فناوری پردیس» واقع شهر پردیس استان تهران نیمه دوم سال 1399 موردبررسی قرار گرفت. به‌منظور جمع‌آوری داده‌ها ابزار پرسشنامه ...