We discuss methodology for multidimensional scaling (MDS) and its implementation in two software systems, GGvis and XGvis. MDS is a visualization technique for proximity data, that is, data in the form of N × N dissimilarity matrices. MDS constructs maps (“configurations,” “embeddings”) in IRk by interpreting the dissimilarities as distances. Two frequent sources of dissimilarities are high-dim...

although aplastic anemia (aa) and myelodysplastic syndrome (mds) are separate entities with different management, distinction between the two can be difficult on morphological basis due to hypocellularity of bone marrow. mds is one of the serious complications of aa. karyotyping is definitive in the diagnosis of mds. better and robust investigations like 18f-fluoro-deoxy-glucose positron emissi...

There remains a useful relation between diffusion and mobility for a Langevin particle in a periodic medium subject to nonconservative forces. The usual fluctuationdissipation relation easily gets modified and the mobility matrix is no longer proportional to the diffusion matrix, with a correction term depending explicitly on the (nonequilibrium) forces. We discuss this correction by considerin...

Group classification of systems of two coupled nonlinear reaction-diffusion equation with a diagonal diffusion matrix is carried out. Symmetries of diffusion systems with singular diffusion matrix and additional first order derivative terms are described.

Genomic instability induces an accumulation of genetic changes and may play a role in the pathogenesis of myelodysplastic syndromes (MDS). To clarify the possible association between genomic instability and clinical outcome in MDS patients, we compared telomere dynamics to the recently established International Prognostic Scoring System (IPSS) risk groups for MDS. We measured the terminal restr...

Myelodysplastic syndrome (MDS) with hypocellular bone marrow (BM) is often difficult to distinguish from aplastic anemia (AA). Furthermore, the diagnosis of MDS with low blast counts and normal karyotype may be problematic. These issues highlight the need for a reliable marker for the diagnosis of MDS. This study was conducted to determine if changes of mRNA expression in any of the four select...

In this work, we propose MDS-Tree and MDS-Matrix as novel high dimensional data visualization methods to gain insight in both the data aspect and dimension aspect of the data. Dimension metrics of the high dimensional dataset are first computed to create a hierarchy. In an MDS-Tree, each node is an MDS projection of the original data items on a specific subset of dimensions associated with the ...

OBJECTIVE [corrected] To determine the clinical characteristics of patients with myelodysplastic syndrome (MDS)-associated Behçet's disease (BD) in Japan. METHODS 54 Japanese cases of MDS-associated BD obtained from the literature and from our own clinical experience were reviewed. The clinical features of MDS-associated BD were compared with those of the 1991 nationwide BD survey in Japan. ...

Abstract Background Myelodysplastic syndrome (MDS), a heterogeneous group of hematopoietic malignancy, has been shown to present different cytogenetic abnormalities, risk factors, and clinico-hematological features in populations geographic areas. Herein, we determined the spectrum Iranian MDS patients for first time. Methods This prospective cross-sectional study was conducted on 103 with Ahva...