We analyze the dynamics of neutral black rings in Taub-NUT spaces and their relation to systems of D0 and D6 branes in the supergravity approximation. We employ several recent techniques, both perturbative and exact, to construct solutions in which thermal excitations of the D0-branes can be turned on or off, and the D6-brane can have Bfluxes turned on or off in its worldvolume. By explicit cal...

A subset of CC chemokines, acting through CC chemokine receptors (CCRs) 1 to 5, is instrumental in shaping inflammatory responses. Recently, we and others have demonstrated that the atypical chemokine receptor D6 actively sequesters and destroys many of these proinflammatory CC chemokines. This is critical for effective resolution of inflammation in vivo. Inflammation can be protumorigenic, and...

We study the open-string moduli of supersymmetric D6-branes, addressing both the string and field theory aspects of D6-brane splitting on Type IIA orientifolds induced by open-string moduli Higgsing (i.e., their obtaining VEVs). Specifically, we focus on the Z 2 × Z 2 ori-entifolds and address the symmetry breaking pattern for D6-branes parallel with the orientifold 6-planes as well as those po...

Primitive hematopoietic progenitor cells (HPCs) are potential targets for treatment of numerous hematopoietic diseases using retroviral-mediated gene transfer (RMGT). To achieve high efficiency of gene transfer into primitive HPCs, a delicate balance between cellular activation and proliferation and maintenance of hematopoietic potential must be established. We have demonstrated that a subpopul...

We present an M-theory proof of the anomaly of Freed and Witten which in general shifts the quantisation law for the U(1) gauge field on a D6-brane. The derivation requires an understanding of how fields on the D6-brane lift to Mtheory, together with a localisation formula which we prove using a U(1)-index theorem. We also show how the anomaly is related to the K-theory classification of Ramond...

Dodecamethylcyclohexasiloxane (D6) is widely used daily in the chemical industry and exists environment; however, its eco-toxicity not well documented. A hydroponic experiment was performed to investigate effects of D6 exposure (10–1000 mg L−1) on oxidative stress induction gene expression changes crayfish (Procambarus clarkii). The results showed that superoxide dismutase (SOD) activity enhanc...

The role of domain 5 (d5) from the self-splicing group II intron 5 gamma of the COXI gene of yeast mitochondrial DNA in branching and 3' splice site utilization has been studied using a substrate transcript lacking d5 (delta d5 RNA). This RNA is completely unreactive in vitro, but releases 5' exon by hydrolysis under various reaction conditions when d5 RNA is added in trans. Under an extreme re...