In cardiac myocytes, LTCCs (L-type calcium channels) form a functional signalling complex with ryanodine receptors at the JM (junctional membrane). Although the specific localization of LTCCs to the JM is critical for excitation-contraction coupling, their targeting mechanism is unclear. Transient transfection of GFP (green fluorescent protein)-α(1S) or GFP-α(1C), but not P/Q-type calcium chann...

A slightly yellow bacterial strain (JM-87(T)), isolated from the stem of healthy 10 day-old sweet corn (Zea mays), was studied for its taxonomic allocation. The isolate revealed Gram-stain-negative, rod-shaped cells. A comparison of the 16S rRNA gene sequence of the isolate showed 99.1, 97.8, and 97.4% similarity to the 16S rRNA gene sequences of the type strains of Elizabethkingia anophelis, E...

This paper describes a genetically guided approach to optimizing the hard (J1) and fuzzy (Jm) c-means functionals used in cluster analysis. Our experiments show that a genetic algorithm ameliorates the di culty of choosing an initialization for the c-means clustering algorithms. Experiments use six data sets, including the Iris data, magnetic resonance and color images. The genetic algorithm ap...

Schellackia calotesi n. sp. is described from the Thai agamids Calotes mystaceus and C. versicolor. Schellackia-type sporozoites were recovered from blood and liver of one C. versicolor from Kon Kaen North-East Thailand and two C. mystaceus from Chiang Mai, North Thailand. Specimens of both species were fed on sporozoite infected blood, of these only one C. mystaceus developed endogenous infect...

Supplementary material A. Symmetric tensors A.1. Background Let Rd1⇥···⇥dm be the set of d1⇥ · · ·⇥dm real m-order tensors. In this paper, we focus on cubical tensors, i.e., d1 = · · · = dm = d. We denote the set of m-order cubical tensors by Rd m . We denote the elements of M 2 Rdm by Mj1,...,jm , where j1, . . . , jm 2 [d]. Let = [ 1, . . . , m] be a permutation of {1, . . . ,m}. Given M 2 Rd...

Enteroadherent Escherichia coli (EAEC) strains identified by adherence to HEp-2 tissue culture cells have been incriminated epidemiologically as important etiologic agents of diarrheal disease in both adult travelers and children in developing countries. One strain, JM 221, with no recognized E. coli virulence characteristics other than adherence to HEp-2 cells, caused diarrhea in 5 of 16 volun...

During development, the activity of cadherin cell adhesion molecules is assumed to be regulated to allow for cell rearrangement or translocation. Previous studies suggest that the juxtamembrane (JM) domain of the cadherin cytoplasmic tail, which contains the site for binding to p120ctn, has a regulatory function in this adhesion system. To study the possible role of JM domain-dependent cadherin...

Ethylenediamine platinum(II) malonate [JM-40 (NSC 146 068)] has been selected for clinical studies because of its favorable preclinical toxicity profile as a "second generation" platinum analogue. When compared to cisplatin, JM-40 was less emetic in the ferret and less nephrotoxic in the dog, while its antitumor activity approached that of cisplatin. Twenty-nine patients received 86 courses of ...

Aerial scene classification, which is a fundamental problem for remote sensing imagery, can automatically label an aerial image with a specific semantic category. Although deep learning has achieved competitive performance for aerial scene classification, training the conventional neural networks with aerial datasets will easily stick in overfitting. Because the aerial datasets only contain a f...

In this study, we have applied the modified exp -expansion function method (MEFM) to obtain exact travelling wave solutions for (3+1) dimensional Khokhlov–Zabolotskaya–Kuznetsov (KZK) equation and (3+1)-dimensional Jimbo-Miwa (JM) equation. Dark soliton solution, dark-bright hyperbolic solution trigonometric of KZK JM been found by using method. After that, scratched 2D 3D graphs all obtained i...