Livestock infection by the parasitic fluke Fasciola hepatica causes major economic losses worldwide. The excretory-secretory (ES) products produced by F. hepatica are key players in understanding the host-parasite interaction and offer targets for chemo- and immunotherapy. For the first time, subproteomics has been used to compare ES products produced by adult F. hepatica in vivo, within ovine ...

Fasciolosis, caused by the trematode Fasciola hepatica, is a zoonosis of economic importance in livestock that is emerging as a chronic disease in humans. The intermediate hosts are lymnaeid snails, in which diagnosis of infection is traditionally based on cercarial shedding, tissue sectioning and crushing. We developed a PCR assay for the sensitive and specific detection of F. hepatica in fiel...

Fasciola hepatica, also known as the liver fluke, is a trematode that infects livestock and humans causing fasciolosis, a zoonotic disease of increasing importance due to its worldwide distribution and high economic losses. This parasite immunoregulates the host immune system by inducing a strong Th2 and regulatory T immune response by immunomodulating dendritic cell (DC) maturation and alterna...

The liver fluke, Fasciola hepatica, is considered as the most common cause of fasciolosis in both domestic livestock and human. This study was carried out to detect the prevalence of the larval stages of F. hepatica in the snails Galba truncatula and Lymnaea stagnalis in West Azarbaijan, Iran. Snail collection was performed through searching 28 freshwater habitats from May to December 2010. Fol...

fasciola hepatica (f. hepatica) as a foodborne trematode can occasionally cause hepatobiliary diseases. we report a 67-year-old woman who was referred to our center because of the diagnosis of cholangitis. she was a resident of mountainous area with the history of unsafe water and contaminated vegetables. endoscopic retrograde cholangiopancreatography (ercp) was performed as a diagnostic and th...

Fasciola hepatica (F. hepatica) as a foodborne trematode can occasionally cause hepatobiliary diseases. We report a 67-year-old woman who was referred to our center because of the diagnosis of cholangitis. She was a resident of mountainous area with the history of unsafe water and contaminated vegetables. Endoscopic retrograde cholangiopancreatography (ERCP) was performed as a diagnostic and th...

In many infection experiments attention has been focused mainly on the rate of the larval development of F. hepatica and the number of rediae and mature cercariae produced by infected L. truncatula (Kendall, 1949; Roberts, 1950; Boray, 1969). Very little consideration has been given to the actual numbers of cercariae which emerge from infected snails. Knowledge of the output of cercariae from i...