Abstract Background The human T-cell lymphotropic virus (HTLV) infects a type of white blood cell called or T-lymphocyte. There are two types HTLV, HTLV-I and HTLV-II, which closely related to C retroviruses. is endemic in the Caribbean, Japan, South America, parts Africa. has been recognized as cause adult leukemia (ATL) HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-I...

Abstract Background Frequent and rapid development of myelopathy has been reported in individuals with human T-lymphotropic virus type 1 (HTLV-1) infection following solid organ transplantation. There is no information regarding HTLV-2, a closely related that often infects injection drug users. Methods This study includes retrospective analysis all consecutive transplants performed during the l...

Recombinant retroviruses containing the trans activator genes of human T-cell leukemia virus (HTLV) type II and human T-cell lymphotropic virus type III were constructed. The trans activator genes tat II and tat III were inserted into the murine retroviral vector pZIPNEOSV(X)1. Recombinant plasmids were transfected into the psi 2 and psi AM packaging cell lines that produce murine leukemia viri...

Abstract Background Human T-lymphotropic virus 1 (HTLV-1) is etiologically associated with the chronic inflammatory neurodegenerative disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) Annexin A1 (AnxA1) an anti-inflammatory protein proposed neuroprotective and anti-neuroinflammatory functions. We hypothesized that ANXA1 gene expression may be dysregulated in HTLV-1-inf...

Human T-lymphotropic virus type 1 (HTLV-1) infection has been discovered recently in people of Amerindian descent living in coastal areas of British Columbia, Canada. DNA sequencing combined with phylogenetic analysis and restriction fragment length polymorphism (RFLP) typing of HTLV-1 strains recovered from these British Columbia Indians (BCI) was conducted. Sequence-based phylogenetic trees d...

The T-cell tropic retrovirus of macaque monkeys STLV-III has morphologic, growth, and antigenic properties indicating that it is related to HTLV-III/LAV, the etiologic agent of the acquired immune deficiency syndrome (AIDS) in humans. Four of six rhesus monkeys died within 160 days of STLV-III inoculation with a wasting syndrome, opportunistic infections, a primary retroviral encephalitis, and ...


 Introducción: La paraparesia espástica es una infección causada por el virus linfotrópico de células T humanas (HTLV-1). Se caracteriza mielopatía lenta instauración que compromete principalmente los miembros inferiores. Afecta más a mujeres varones y las principales vías transmisión son: sanguínea, sexual vertical (principalmente durante la lactancia).
 Presentación del caso: Gesta...