Recently, in the field of ITS (Intelligent Transportation System), accurate and precise position of a vehicle in the street is more demanding. They want to know which lane a car is driving in. The GNSS RTK could provide this accuracy. But, in urban street, due to its environment, the conventional code and carrier based RTK can’t be a practical solution. The Doppler measurement from GNSS receive...

RTK pathways establish cell fates in a wide range of developmental processes. However, how the pathway effector MAPK coordinately regulates the expression of multiple target genes is not fully understood. We have previously shown that the EGFR RTK pathway causes phosphorylation and downregulation of Groucho, a global co-repressor that is widely used by many developmentally important repressors ...

Growth factor receptor tyrosine kinase (RTK)-activated signaling pathways are well established regulators of neuronal growth and development, but whether these signals provide mechanisms for acute modulation of neuronal activity is just beginning to be addressed. We show in pheochromocytoma (PC12) cells that acute application of ligands for both endogenous RTKs [trkA, basic FGF (bFGF) receptor,...

Epithelial Na Channels (ENaC) are responsible for the apical entry of Na(+) in a number of different epithelia including the renal connecting tubule and cortical collecting duct. Proteolytic cleavage of γ-ENaC by serine proteases, including trypsin, furin, elastase, and prostasin, has been shown to increase channel activity. Here, we investigate the ability of another serine protease, tissue ka...

A displacement measurement system fusing a low cost real-time kinematic global positioning system (RTK-GPS) receiver and a force feedback accelerometer is proposed for infrastructure monitoring. The proposed system is composed of a sensor module, a base module and a computation module. The sensor module consists of a RTK-GPS rover and a force feedback accelerometer, and is installed on a target...

Receptor tyrosine kinases (RTK) or ligands have frequent genetic alterations in cancers. Either amplifications, missense mutations fusions of RTK are biomarkers for some targeted therapies a fraction cancers, with heterogeneous responses to kinase inhibitors (TKI), monoclonal antibodies (mabs) andibody-drug conjugates (ADC). An analysis pan-cancer molecular and clinical outcome RTK-altered canc...

Abstract. PPP-RTK has been widely investigated to take the advantages of both real-time kinematic (RTK) and precise point positioning (PPP) techniques. Prior PPP-RTK, conventional RTK based on use a single base station, one hand, extended work within regional network multiple stations, known as (NRTK). The NRTK enable fast ambiguity resolution over short baseline or local region. PPP, other eli...

The receptor tyrosine kinase (RTK) signaling pathway is used reiteratively during the development of all multicellular organisms. While the core RTK/Ras/MAPK signaling cassette has been studied extensively, little is known about the nature of the downstream targets of the pathway or how these effectors regulate the specificity of cellular responses. Drosophila yan is one of a few downstream com...

Dual-frequency Global Positioning System (GPS) Real-time Kinematics (RTK) has been proven in the past few years to be a reliable and efficient technique to obtain high accuracy positioning. However, there are still challenges for GPS single-frequency RTK, such as low reliability and ambiguity resolution (AR) success rate, especially in kinematic environments. Recently, multi-Global Navigation S...