Gestation and delivery can increase intra-abdominal pressure, which are well-known risk factors for Pelvic Organ Prolapse (POP). But the pathogenesis mechanism of POP remains unclear. Our previous research showed that the expression of glutathione peroxidase type 1 (GPX1) decreased in pelvic floor ligaments from POP patients, implying that oxidative stress (OS) may be related to POP. The aim of...

Population-III (Pop-III) starformation (SF) is thought to be quenched when the metallicity of the starforming gas has reached a critical level. At high redshift, when the general intergalactic medium (IGM) was enriched with metals, the fraction of primordial gas already collapsed in minihalos (above the Jeans mass but below the mass corresponding to the efficient atomic cooling threshold for SF...

In this study, we aim to conduct usability tests on different WebMap sites with eye movement analysis. Overall task performance, the effects of iconic representation of information, and the efficiency of pop-up usage were evaluated. The eye tracking technology is used for this study in order to follow the position of the users’ eye-gaze. The results show that there are remarkable differences in...

The aim of this paper is to examine the parallelism between tonal transitions and musical note transitions in Thai pop songs based on the data from 30 current pop songs. The results suggest that there is a statistically significant parallelism between tonal transitions and musical note transitions. Interestingly, the results show that both contour tones, RISING and FALLING, typically pattern wi...

POP-1, a Tcf/Lef-1-like target of the convergent Wnt and MAP kinase (MAPK) signaling pathways, functions throughout Caenorhabditis elegans development to generate unequal daughters during asymmetric cell divisions. A particularly prominent such asymmetric division occurs when the EMS blastomere divides to produce MS, a mesoderm precursor, and E, the sole endoderm progenitor. POP-1 allows mesode...

We present a new bound for the worldvolume actions of branes with a Wess-Zumino term. For this we introduce a generalization of calibrations for which the calibration form is not closed. We then apply our construction to find the M-5-brane worldvolume solitons in an AdS background that saturate this bound. We show that these worldvolume solitons are supersymmetric and that they satisfy differen...

Many neurons in visual area V1 respond better to a pop-out stimulus, such as a single vertical bar among many horizontal bars, than to a homogeneous stimulus, such as a stimulus with all vertical bars. Many studies have suggested such cells represent neural correlates of pop-out, or more generally figure-ground segregation. However, preference for pop-out stimuli over homogeneous stimuli could ...

Pelvic organ prolapse (POP) is a common condition affecting almost half of women over the age of 50. The molecular and cellular mechanisms underlying this condition, however, remain poorly understood. Here we have reported that fibulin-5, an integrin-binding matricellular protein that is essential for elastic fiber assembly, regulated the activity of MMP-9 to maintain integrity of the vaginal w...

OBJECTIVE Homeobox genes are transcriptional regulators that orchestrate embryonic development. The HOXA13 gene is responsible for the development of the vagina and regulates extracellular matrix constituents. We hypothesized that vaginal expression of HOXA13 may be decreased in women with pelvic organ prolapse (POP) and sought to determine if hypoestrogenism affects its expression. METHODS B...