AIMS   The optimal method for diagnostic collection of urine in children is unclear. National Institute of Health and Clinical Excellence recommend specimens taken by clean catch urine (CCU) for identification of urinary tract infection (UTI). We investigated contamination rates for CCU, suprapubic aspiration (SPA), catheter specimen urine (CSU) and bag specimen urine (BSU) collections. METHO...

We develop a microeconomic model of endogenous growth where clean and dirty technologies compete in production and innovation– in the sense that research can be directed to either clean or dirty technologies. If dirty technologies are more advanced to start with, the potential transition to clean technology can be diffi cult both because clean research must climb several rungs to catch up with ...

In response to widespread policy prescriptions for responsible innovation, social scientists and engineering ethicists, among others, have sought to engage natural scientists and engineers at the 'midstream': building interdisciplinary collaborations to integrate social and ethical considerations with research and development processes. Two 'laboratory engagement studies' have explored how appl...

In a retrospective review of 32 consecutive patients (20 adults and 12 children) with acute appendicitis, we correlated abnormal urinalysis with the operative findings. Abnormal results on urinalysis were noted in 10 adults and 5 children. All urine specimens were collected by the clean-catch method. Abnormal findings were found more frequently in female patients. The majority of the patients w...

Gram-positive, catalase-positive cocci (Micrococcaceae) have been obtained from the bladder by suprapubic aspiration of urine in antenatal and postnatal patients. These bacteria have been compared with similar organisms isolated from midstream specimens of urine when the suprapubic specimen was sterile. Fourteen (70%) of 20 organisms isolated from the bladder were micrococci and six (30%) were ...