Introduction: Because of small size of the beamlets in IMRT, physical penumbra is one of the important dosimetric parameters and small changes in the penumbra will have a great impact on the results. The physical penumbra width is defined as the lateral distance between two specified isodose curves at a specified depth of phantom. In this study, after demonstrating the inconsi...

Background: Midwifery led care (MLC) is a model of care in which perinatal care is provided to women throughout different phases of childbirth by a midwife. Objective: This paper aims to provide a literature review on MLC. Methods: A variety of databases and reports were considered to do the literature review on MLC. The search was limited from 1991 to 2011 by using keywords. A total of 50 arti...

7 In this paper, we propose a cancellable fingerprint template technique based on our previous work on multi-line code (MLC) (Wong et al., 2012). The modification and improvement focuses on the change of MLC values and the generation of binary MLC. In addition, an enhanced similarity measure is also proposed to compensate the loss in accuracy for binary MLC, called the dynamically weighted inte...

The mixed lymphocyte culture (MLC) test has been regarded as an in vitro model of the recognition or sensitization phase of the homograft or graft-versus-host reaction. It has been suggested that the graft-versus-host response in vivo is less in xenogeneic combinations than in allogeneic ones and that there is a similar quantitative relationship in MLC responses. Given the above interpretation ...

Although it is well known that mutations in the cardiac regulatory myosin light chain-2 (mlc-2) gene cause hypertrophic cardiomyopathy, the precise in vivo structural and functional roles of MLC-2 in the heart are only poorly understood. We have isolated a mutation in zebrafish, tell tale heart (tel(m225)), which selectively perturbs contractility of the embryonic heart. By positional cloning, ...

Isometrically suspended uteri from estrogen-primed rats were stimulated with prostaglandin F2 alpha and then exposed to relaxin. Relaxin-dependent decreases in the ratio of phosphorylated to total myosin light chains (MLC) and in MLC kinase activity, measured in the presence of 0.5 mg/ml of uterine myosin and the absence and presence of Ca2+-calmodulin (CaM), were observed. The time-course and ...

Mechanisms of Ca2+ sensitization of both myosin light chain (MLC) phosphorylation and force development by protein kinase C (PKC) were studied in permeabilized tonic smooth muscle obtained from the rabbit femoral artery. For comparison, the Ca2+ sensitizing effect of guanosine 5'-O-(gamma-thiotriphosphate) (GTP gamma S) was examined, which had been previously shown to inhibit MLC phosphatase in...

OBJECTIVES The impact of two multileaf collimator (MLC) systems for linear accelerator-based intracranial stereotactic radiosurgery (SRS) was assessed. METHODS 68 lesions formed the basis of this study. 2.5 mm leaf width plans served as reference. Comparative plans, with identical planning parameters, were based on a 5 mm leaf width MLC system. Two collimation strategies, with collimation fix...

Both Rho-kinase and the Ca(2+)/calmodulin-dependent myosin light chain (MLC) kinase increase the phosphorylation of MLC. We show that upon thrombin receptor stimulation by low-dose thrombin or the peptide ligand YFLLRNP, or upon thromboxane receptor activation by U46619, shape change and MLC phosphorylation in human platelets proceed through a pathway that does not involve an increase in cytoso...