Adult Ibsp-knockout mice (BSP-/-) display shorter stature, lower bone turnover and higher trabecular bone mass than wild type, the latter resulting from impaired bone resorption. Unexpectedly, BSP knockout also affects reproductive behavior, as female mice do not construct a proper "nest" for their offsprings. Multiple crossing experiments nonetheless indicated that the shorter stature and lowe...

BACKGROUND Bone sialoprotein (BSP), a bone matrix protein, was recently found to be expressed ectopically in breast cancer and to have a statistically significant association with poor prognosis and the development of bone metastases in that disease. These data prompted us to investigate whether BSP might also be expressed in human prostate cancer, which often metastasizes to bone, and be predi...

The bulk synchronous parallel (BSP) is a celebrated synchronization model for general-purpose computing that has successfully been employed distributed training of deep learning models. A shortcoming the BSP it requires workers to wait straggler at every iteration. Therefore, employing increases waiting time faster cluster and results in an overall prolonged time. To ameliorate this BSP, we pro...

We investigate the problem of autonomous object classification and semantic SLAM, which generally exhibits a tight coupling between classification, metric planning under uncertainty. contribute unified framework for inference belief space (BSP) that addresses prominent sources uncertainty in this context: aliasing (classifier cannot distinguish candidate classes from certain viewpoints), classi...

In this paper general simulations of algorithms designed for fully operational BSP machines on BSP machines with faulty processors or unavailable processors are developed. The fail-stop model is considered, that is, if a processor fails or becomes unavailable it remains so until the end of the computation. The faults are random, that is, a processor may fail independently with probablility a, a...

Bone sialoprotein (BSP) and osteopontin (OPN) are both highly expressed in bone, but their functional specificities are unknown. OPN knockout (-/-) mice do not lose bone in a model of hindlimb disuse (tail suspension), showing the importance of OPN in bone remodeling. We report that BSP(-/-) mice are viable and breed normally, but their weight and size are lower than wild-type (WT) mice. Bone i...

0.05) in odor between treatments and the control BSP pieces for all storage days. Lactic acid treated BSP pieces were more likely to be lighter, greener, and more yellow throughout the storage period when compared to control BSP pieces. Lower microbial counts and indistinguishable odor differences were achieved with 2.00% LA treated BSP pieces. Using 2.00% LA in beef trimmings may provide a mic...

About 1 in 3 people suffer from bone and joint disease, which is a disease of bone and cartilage cells. Osteonecrosis of the femoral head (ONFH) is a typical example of bone and joint disease involving bone cell necrosis. Osteonecrosis of the femoral head leads to the occurrence of premature osteoarthritis of the hip and collapse of the cartilage cells, and there is currently no effective drug ...

The search for a protein nucleator of hydroxyapatite crystal formation has been a focus for the isolation and characterization of the major non-collagenous proteins in bone. Of the proteins characterized to date, bone sialoprotein (BSP) has emerged as the only bona fide candidate for nucleation. BSP is a highly glycosylated and sulphated phosphoprotein that is found almost exclusively in minera...

BACKGROUND It has been suggested that host matrix metalloproteinase-2 (MMP-2) present in dentin may be involved in caries progression, however, its response to caries is not known. Bone sialoprotein (BSP) has been implicated in dentin mineralization and MMP-2 modulation. OBJECTIVE To identify and compare the distribution of MMP-2 and BSP in healthy human coronal dentin and those with early ca...