BACKGROUND Scleredema adultorum of Buschke is an uncommon skin condition that may accompany diabetes mellitus. Current therapeutic options are poor, with only case reports and small series supporting their use. OBSERVATION We describe 3 patients with severe restrictive scleredema associated with type 2 diabetes mellitus who responded to radiation therapy after other treatments had failed. Ang...

1Department of General Surgery, Proctology Unit, Solec Hospital, Warsaw Head of Department: Jacek Bierca, MD, PhD Head of Unit: Małgorzata Kołodziejczak, MD, PhD 2Pathology Department, Central Clinical, Hospital of Ministry of Interior and Administration, Warsaw Head of Department: prof. Anna Nasierowska-Guttmejer, MD, PhD 3Faculty of Health Sciences, Department of Pathology, Jan Kochanowski Un...

Magnetic resonance based volumetric measures of hippocampal formation, amygdala (A), caudate nucleus (CN), normalised for total intracranial volume (TIV), were analysed in relation to measures of cognitive deterioration and specific features of memory functions in 18 patients with probable Alzheimer's disease. Neuropsychological examination included the mini mental state examination (MMSE), the...

Abstract We present a case of Buschke–Ollendorff syndrome (BOS) in 6-year-old girl. The BOS is rare genodermatosis distinguished by the presence short stature and skeletal connective tissue defects. This patient first attended dermatology department with history small asymptomatic dermal papules nodules noted overlying skin on her abdomen since age 2 years. They became more numerous evolved ove...

Punctate palmoplantar keratoderma type 1, also known as Brauer-Buschke-Fisher syndrome, is an autosomal dominant inherited disorder with variable penetrance. The disorder is characterized by multiple punctate hyperkeratotic papules on the palms and soles. Although it is a clinical rarity, a spot diagnosis can usually be made provided one is familiar with the condition thereby unnecessary diagno...

Dear Editor, Giant condyloma acuminate (GCA) fi rst described by Buschke, also known as Buschke-Löwenstein tumour (BLT), is a slow growing, semi malignant neoplasm of the external genitalia and perianal region that has a recurrence tendency.1 Inspite of its histologically benign appearance, BLT clinically behaves in a malignant fashion, destroying adjacent tissues, and is reported as an entity ...