We investigated whether the VP1 protein of simian virus 40 binds to DNA. In vitro DNA-binding experiments clearly indicate that VP1 bound strongly to double-stranded and single-stranded DNA, with a higher affinity for the latter; additional experiments show that VP1 did not bind to a specific sequence of simian virus 40 DNA.

Treatment with interferon reduced the content of early virus-specific RNA, as well as the content of an early viral protein (T antigen), in monkey cells acutely infected with simian virus 40 (SV40). This unexpected finding suggests either that the action of interferon involves inhibition of the transcription of early SV40 messenger RNA, or that the SV40 genome contains a "proto-early" gene whos...

Recent developments are summarized in the theory of Bose– Einstein and Fermi–Dirac correlations, with emphasis on the necessity of a simultaneous analysis of particle spectra and quantum statistical correlations for a detailed reconstruction of the space-time picture of particle emission. The reviewed topics are as follows: basics and formalism of quantum-statistical correlations, model-indepen...

introduction: present children are the investments of community in the future. preparing children health which leads to the stability of community health, provided to accurate implementation of educational and health programs in the community and especially in mothers. so it is necessary to determine the relationship between parents' literacy with growth rate in children.   materials and m...

adenoviruses are one of the most important etiological agents of serious gastroenteritis among infants and young children. fecal specimens from patients with an acute gastroenteritis were evaluated for the presence of adenovirus (ad40, 41) from april 2002 to february 2004. during the study, 1052 samples were collected from children under the age of 5 years in six educational and therapeutic ped...