Nucleoplasmin is a histone chaperone that consists of a pentameric N-terminal domain and an unstructured C-terminal tail. The pentameric core domain, a doughnut-like structure with a central pore, is only found in the nucleoplasmin family. Here, we report the first structure of a nucleoplasmin-like domain (NPL) from the unrelated Drosophila protein, FKBP39, and we present evidence that this pro...

This study aims to analyze the effect of Loan Deposit Ratio (LDR) and Earning Asset Quality (EAQ) on Non-Performing (NPL) before during Covid-19 pandemic. The data used in this are quarterly reports rural banks Central Java from 174 banks. Data analysis was carried out by comparing multiple linear regressions results show that pandemic can strengthen negative relationship between LDR NPL, as we...

Analogous to the epidemiology of different types of human papillomaviruses (HPVs), variants of a single type such as HPV16 may differ in the natural course of infection. A prospective study was conducted in a cohort of female university students who did not have HPV16 DNA or antibody at enrollment. Subjects were followed every 4 months with Pap smear and colposcopic examinations and tests for H...

BACKGROUND Over the last two decades, various spatial techniques have been demonstrated using geographical information systems (GIS) to adequately estimate and characterize inequities of minority populations living near environmentally hazardous facilities. However, these methods have produced mixed results. In this study, we use recently developed variations of the "distance based" approach to...

Objectives To describe the incidence and determinants of survival of patients with nasopharyngeal lymphoma (NPL) between 1973 and 2012 using the Surveillance, Epidemiology, and End Results (SEER) database. Study Design Retrospective cohort study using a national database. Methods The SEER registry was used to calculate survival trends for patients with NPL between 1973 and 2012. Patient data we...

The problem of the Chinese financial system with non performing loans is significant and murky. If China's non performing loan problem exists on a certain level of severity and is not trending toward a more manageable state, then China could be moving toward financial crisis. Empirical and theoretical studies in recent years have implied that this might be the case. It might be impossible to co...

Parametric and nonparametric statistical methods have been applied to the alcohol dependence dataset collected in the Collaborative Study on the Genetics of Alcoholism (COGA). Our nonparametric linkage analyses (NPL) were based on the Sall statistic of GENEHUNTER [Kruglyak et al., 1996] and the improved NPL statistic of GENEHUNTER-Plus [Kong and Cox, 1997]. Based on likely regions for alcohol s...

A Strategic Research project was performed at NPL with the aim of investigating issues and potential improvements for light-ion dosimetry. The objectives of the project were: a literature survey, testing a number of dosimeters in the proton therapy beam of Clatterbridge Centre of Oncology (CCO), measurement of dose distributions, measurement and calculation of detector perturbations, explore th...