AKI YAMADA,1 SUSUMU OHYA,2 MASARU HIRANO,2 MINORU WATANABE,2 MICHAEL P. WALSH,3 AND YUJI IMAIZUMI1 1Department of Pharmacology and Therapeutics and 2Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan; and 3Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Ca...

Eaton, Philip, Jian-Mei Li, David J. Hearse, and Michael J. Shattock. Formation of 4-hydroxy-2-nonenalmodified proteins in ischemic rat heart. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H935–H943, 1999.—4-Hydroxy-2nonenal (HNE) is a major lipid peroxidation product formed during oxidative stress. Because of its reactivity with nucleophilic compounds, particularly metabolites and proteins co...

Kocsis, Bernat, Tomas Karlsson, and B. Gunnar Wallin. Cardiacand noncardiac-related coherence between sympathetic drives to muscles of different human limbs. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1608–R1616, 1999.—Partial coherence analysis was used to evaluate the extent to which coherence between resting muscle sympathetic activity (MSA) in different pairs of limbs ...

Wyman, Bradley T., William C. Hunter, Frits W. Prinzen, and Elliot R. McVeigh. Mapping propagation of mechanical activation in the paced heart with MRI tagging. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H881–H891, 1999.— The temporal evolution of three-dimensional (3-D) strain maps derived from magnetic resonance imaging (MRI) tagging were used to noninvasively evaluate mechanical activati...

Kozma, Fruzsina, Robert A. Johnson, Fan Zhang, Changhua Yu, Xianglan Tong, and Alberto Nasjletti. Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1087–R1094, 1999.— Endogenous carbon monoxide was proposed to subserve vasodepressor functions. If so, inhibition of heme oxygenase may be exp...

Hypertension is the most common medical disorder of pregnancy in the United States, affecting 6% to 8% of pregnant women. It is also a leading cause of maternal and fetal morbidity and mortality worldwide1; approximately 63,000 women die every year because of the maternal hypertensive syndromes preeclampsia and eclampsia.2 Hypertensive disorders also result in fetal complications such as preter...

Villalobos, Alice R., Judith T. Parmelee, and J. Larry Renfro. Choline uptake across the ventricular membrane of neonate rat choroid plexus. Am. J. Physiol. 276 (Cell Physiol. 45): C1288–C1296, 1999.—The uptake of [3H]choline from the cerebrospinal fluid (CSF) side of the rat neonatal choroid plexus was characterized in primary cultures of the choroidal epithelium grown on solid supports. Cell-...

Currie, Suzanne, Bruce L. Tufts, and Christopher D. Moyes. Influence of bioenergetic stress on heat shock protein gene expression in nucleated red blood cells of fish. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R990–R996, 1999.—The physiological and biochemical signals that induce stress protein (HSP) synthesis remain conjectural. In this study, we used the nucleated red bl...

Boulton, M., M. Flessner, D. Armstrong, R. Mohamed, J. Hay, and M. Johnston. Contribution of extracranial lymphatics and arachnoid villi to the clearance of a CSF tracer in the rat. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R818–R823, 1999.—The objective of this study was to determine the relative roles of arachnoid villi and cervical lymphatics in the clearance of a cereb...

Moran, Daniel S., Yair Shapiro, Arie Laor, Sharona Izraeli, and Kent B. Pandolf. Can gender differences during exercise-heat stress be assessed by the physiological strain index? Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1798–R1804, 1999.—A physiological strain index (PSI) based on rectal temperature (Tre) and heart rate (HR) was recently suggested to evaluate exercise-he...