Genome-wide association (GWA) study aims to identify the genetic factors associated with the traits of interest. However, the power of GWA analysis has been seriously limited by the enormous number of markers tested. Recently, the gene set analysis (GSA) methods were introduced to GWA studies to address the association of gene sets that share common biological functions. GSA considerably increa...

We examine the lived experiences of high-school students who participated in lesbian, gay, bisexual, transgender, and queer (LGBTQ)-centered activism of some kind, highlighting the promise of gay-straight alliance groups by comparing the experiences of students at schools with gay-straight alliances (GSA schools) with the experiences of students at schools that did not have an LGBTQ-specific gr...

In this paper, we propose an improved gravitational search algorithm named GSABC. The algorithm improves gravitational search algorithm (GSA) results improved by using artificial bee colony algorithm (ABC) to solve constrained numerical optimization problems. In GSA, solutions are attracted towards each other by applying gravitational forces, which depending on the masses assigned to the soluti...

Near-infrared photoimmunotherapy (NIR-PIT) is a highly cell-selective cancer therapy based on an armed antibody conjugated with a phthalocyanine-based photo-absorber, IRDye700DX (IR700). NIR-PIT can quickly kill target cells that express specific proteins on the cellular membrane but only when the antibody-IR700 conjugate binds to the cell membrane and is then exposed to NIR light. NIR-PIT is h...

gravitational search algorithm (gsa) is one of the newest swarm based optimization algorithms, which has been inspired by the newtonian laws of gravity and motion. gsa has empirically shown to be an efficient and robust stochastic search algorithm. since introducing gsa a convergence analysis of this algorithm has not yet been developed. this paper introduces the first attempt to a formal conve...

A hybrid meta-heuristic optimization method is introduced to efficiently find the optimal shape of concrete gravity dams including dam-water-foundation rock interaction subjected to earthquake loading. The hybrid meta-heuristic optimization method is based on a hybrid of gravitational search algorithm (GSA) and particle swarm optimization (PSO), which is called GSA-PSO. The operation of GSA-PSO...

Gene set enrichment analysis (GSA) methods have been widely adopted by biological labs to analyze data and generate hypotheses for validation. Most of the existing comparison studies focus on whether the existing GSA methods can produce accurate P-values; however, practitioners are often more concerned with the correct gene-set ranking generated by the methods. The ranking performance is closel...

Gravitational Search Algorithm (GSA) is a newly heuristic algorithm inspired by nature which utilizes Newtonian gravity law and mass interactions. It has captured much attention since it has provided higher performance in solving various optimization problems. This study hybridizes the GSA and chaotic equations. Ten chaotic-based GSA (GSA-CM) methods, which define the random selections by diffe...