BACKGROUND & OBJECTIVES The emergence of resistance to fluoroquinolones in enteric fever despite the pathogen being susceptible by in vitro laboratory results, led to repeated changes in Clinical and Laboratory Standard Institute (CLSI) guidelines for this class of antibiotics to have specific and sensitive interpretative criteria. In 2015, CLSI added pefloxacin disk diffusion criteria as a sur...

INTRODUCTION Bacterial infections that cause community-acquired urinary tract infections (CA-UTI) and upper respiratory tract infections (CA-URTI) are most frequently treated empirically. However, an increase in antimicrobial resistance has become a problem when treating outpatients. METHODS This study determined the in vitro activities of oral antibiotics among 1501 pathogens from outpatient...

In laboratory medicine, our main goal is to improve patient health by providing laboratory results that support medical decisions. To meet this goal, the laboratory needs to report accurate results that enhance care and minimize patient risk. Analytical goal setting helps the laboratory assure that when their measurement procedures are operating in their stable, in-control state, the patient re...

The nutritional value of raw Jack bean meal (Canavalia ensiformis) as a partial substitute for soybeans meal was investigated in this study. Preliminary investigation on nutrient composition revealed that lysine, histidine, and phenylalanine were significantly higher in C. ensiformis seed meal compared to soybean meal. However, crude protein and other essential amino acids were significantly lo...

بخش اورژانس یکی از شلوغ‌ترین بخش‌های یک بیمارستان است و بهبود عملکرد این تأثیر بسیاری در کیفیت ارائه خدمات دارد. اخیراً پژوهشگران به­‌دلیل تمرکز مهندسی تاب‌آوری مدیریت ناب بر کارایی سیستم‌ها توجه بسیار زیادی به دو دیدگاه کنار یکدیگر داشته‌اند. هدف پژوهش، رویکردی یکپارچه برای ارزیابی مبتنی شاخص‌های با ارتقای رضایت شغلی کاهش هزینه‌های درمانی واحد خصوصی است. منظور، ابتدا شناسایی مؤثر، مدل مفهومی مس...

BACKGROUND AND PURPOSE A simplified antifungal disk diffusion test using Mueller-Hinton agar containing 2% glucose and methylene blue 5 microg/mL (GM-MH, Clinical and Laboratory Standards Institute [CLSI] M44-A) has proved to correlate well with the standard reference test. A new azole, voriconazole, has recently been approved for clinical therapy in Taiwan. This study investigated the reliabil...

Clinical and Laboratory Standards Institute document EP09-A3—Measurement Procedure Comparison and Bias Estimation Using Patient Samples; Approved Guideline—Third Edition is written for laboratorians and manufacturers. It describes procedures for determining the bias between two measurement procedures, and it identifies factors for consideration when designing and analyzing a measurement procedu...

OBJECTIVES The objective of this study was to evaluate the in vitro activity of CD101, a novel echinocandin with a long serum elimination half-life, and comparator (anidulafungin and caspofungin) antifungal agents against a collection of Candida and Aspergillus spp. isolates. METHODS CD101 and comparator agents were tested against 106 Candida spp. and 67 Aspergillus spp. isolates, including 2...

A total of 2484 target bacterial pathogens were collected (one per patient episode) from patients in 16 Latin American medical centers located in seven nations during 2011. Isolate identity was confirmed at a coordinating laboratory and susceptibility testing was performed for ceftaroline and comparator agents according to reference broth microdilution methods. A total of 30.0% of isolates were...