background: the hepatic secretion of apolipoprotein b (apob), containing lipoproteins, is known to be regulated by insulin, and the overproduction of these atherogenic lipoproteins occurs in insulin-resistant states. protein tyrosine phosphatase 1b (ptp-1b) is a key regulator of hepatic insulin signaling and is also upregulated in insulin resistance. we aimed to investigate the role of ptp-1b i...

background: metronidazole, a 5-nitroimidazole derivative, is the main antitrich­omonal agent of  choice   for   treatment  of t richomoniasis . since 1962, s ome cases of treatment failure with metronidazole have been reported and recently drug re­sistance is now on the rise in the world. this study was aimed to determine current susceptibility of iranian isolates of trichomonas vaginalis to me...

background: weak efficacy of different fasciolicidal compounds used for treatment of paramphistomosis has drawn the attention of many authors to alternative drugs. the purpose of this study was to assess, for the first time, the effect of the methanolic extract of balanites aegyptiaca fruits (bae) on adult paramphistomum microbothrium . methods : the effect of bae on adult p. microbothrium afte...

background: the beneficial role of cabergoline as a prophylactic agent to prevent ovarian hyper stimulation syndrome (ohss) among high-risk patients has been demonstrated in previous studies. but data for its role as a treatment for established severe ohss is still limited. we represent the treatment results of high dose oral cabergoline in management of six patients after the syndrome is estab...

background: gonadotrophin-releasing hormone (gnrh) agonist is used for controlling ovarian stimulation in assisted reproductive technology (art) cycles which has some benefits. objective: to compare the efficacy of two different formulations of gnrh agonist: short-acting and long-acting, for art protocols. materials and methods: in a prospective randomized study, one hundred women who underwent...

background: estradiol (e2) is required for follicular development and play an important role in embryo implantation. objective: the aim of this study was to assess the impact of serum e2 levels on the day of hcg administration in ivf-icsi patients who are performed controlled ovarian hyperstimulation (coh). materials and methods: a total of 203 women who were undergone one time ivf cyclus were ...

background   objective:   materials and methods   results   conclusion   key words:   . vitrification, viability, in vitro maturation, gvbd, oocyte, mouse : these results suggest that step-wise vitrification of gvbd oocytes as compared to single step vitrification was better in the rate of survival and in vitro maturation of oocytes. : all non-vitrified oocytes were viable after 24 hr; however,...

background: smoking has negative effects on reproductive process. exposing to cigarette smoking (passive smoking) may exert some effects as the direct smoking. objective: the aim of this study was to evaluate the correlation between ovarian response and passive smoking in women who underwent art cycles. materials and methods: one hundred-sixty patients who underwent icsi between 2000 and 2001 w...

background: although the uterine fibroids are common, their influence on fertility remains controversial. the association of submucosal fibroid with subfertility is well recognized, but debate persists as to whether intramural fibroids can cause infertility and the evidence for its effect on pregnancy in cycles of assisted conception remains unclear. objective: the purpose of present study was ...