It is unclear at present which mathematical modeling Kt/V(urea) is valid for assessment of both long mild hemodialysis (HD) and short intensive HD, the single-pool modeling Kt/V (Kt/Vsp) based on the pre- and postdialysis serum urea concentrations, double-pool modeling Kt/V (Kt/Vdp) based on the predialysis concentration and the estimated postdialysis equilibrated concentration, or Kt/V calcula...

BACKGROUND Healthcare professionals require training in knowledge translation (KT) to implement evidence-based healthcare innovations. Mentorship is an effective training strategy that could be used to develop KT capacity but it has largely been used to train clinicians. The purpose of this study was to explore preferences for KT mentorship design. METHODS Interviews were conducted with 54 Ca...

Background Knowledge translation (KT) refers to the process of moving knowledge into healthcare practice and policy. The practice of KT is about helping decision-makers become aware of knowledge and facilitating their use of it in their day-to-day work. The science of KT is about studying the determinants of knowledge use and investigating strategies to support the adoption, implementation, and...

Knowledge transfer (KT) is an evolutionary process that requires embedding into and assistance from organizational culture. Since the determinants and influence path of KT regarding cultural change are not clear, this study designs a path model from organizational culture to KT through organizational characteristics. The findings demonstrate that the sociability factors of organizational cultur...

Background As the Knowledge Translation (KT) field advances, there is an increasing need to identify priorities to help shape future directions for research. An important source of KT priorities is ‘experts’ who are well-established researchers and practitioners. Another potential source for identifying priorities is trainees. Given that many KT trainees are developing their programs of researc...

Ketorolac tromethamine (KT) containing microemulsion-based gels (MBGs) have been formulated, based on the previous phase diagram studies, using a pharmaceutically acceptable surfactant (soybean lecithin; Epikuron 200) and oil (isopropyl myristate; IPM) and the effect of formulation variables on the release profile of the drug from MBGs through intact guinea pig skin and various artificial membr...

The original formula proposed to estimate variable-volume single-pool (VVSP) Kt/V was Kt/V = -In(R - 0.008 * t - f * UF/W), where in the Kt/V range of 0.7 to 1.3, f = 1.0 (* denotes multiplication). This formula tends to overestimate Kt/V as the Kt/V increases above 1.3. Because higher Kt/V values are now commonly delivered, the validity of both the urea generation term (0.008 * f) and correcti...

BACKGROUND Inadequate dialysis dose is closely related to mortality and morbidity of maintenance haemodialysis (MHD) patients. According to the DOQI guidelines a minimum prescribed dialysis dose of single-pool Kt/V (Kt/Vsp)=1.3, equivalent to equilibrated double pool Kt/V (e-Kt/Vdp)=1.1, is recommended. Knowledge of patient-related risk factors for inadequate delivery of hacmodialysis would be ...