Cholangiocarcinoma (CCA) occurs frequently in primary sclerosing cholangitis (PSC). Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES-1) induced by inflammation are believed to mediate prostaglandin E2 (PGE2) production thereby promoting carcinogenesis. Their expression in PSC-associated CCA tissues and non-neoplastic bile duct epithelial cells (BDECs) in PSC was investi...

There have been conflicting reports as to the extent that copper-chromium-arsenic (CCA) treatments leach from timber. In New Zealand, vineyards utilise CCA-treated posts at a rate of 579 posts per hectare. This represents a potential CCA burden on the soil of 12, 21, and 17 kg/ha, respectively, for the three elements. Given a replacement rate of 4% per year, the use of CCA-treated posts may res...

هدف: این پژوهش با هدف بررسی اثر آموزش برنامه هوش موفق استرنبرگ بر افزایش خلاقیت و تحمل ابهام دانش‌­آموزان انجام شد. روش: روش ­آزمایشی طرح پیش ­آزمون پس پیگیری گروه کنترل بود. جامعۀ آماری را 15842 نفر ازدانش‌­آموزان پسر کلاس چهارم در سال تحصیلی1399-1400 شهر اصفهان تشکیل دادند که30 نمونه‌­گیری تصادفی چند مرحله­‌ای انتخاب به صورت دو آزمایش (15 نفر) گمارده شدند. ده جلسه برنامه‌­ی دریافت نمود. داده­...

Understanding the minimal assumptions from which we can build a publickey encryption scheme secure against chosen-ciphertext attacks (a CCA-secure scheme, for short) is a central question in both practical and theoretical cryptography. Following the large body of work on hardness and correctness amplification, we ask the question of how far we can weaken a CCA-secure encryption scheme so that a...

AIM To determine the clinical and dietary predictors of common carotid artery intima media thickness (CCA IMT) in a cohort of subjects with type 1 and type 2 diabetes. METHODS Participants with type 1 (n = 23) and type 2 diabetes (n = 127) had mean and mean maximum CCA IMT measured using B mode ultrasound. Dietary intake was measured using a food frequency questionnaire. Clinical and dietary ...

BACKGROUND AND AIM Extrahepatic cholangiocarcinoma (CCA) typically presents as biliary strictures. Endoscopic ultrasound (EUS)-fine needle aspiration (FNA) may contribute to the diagnosis of CCA as the etiology of extrahepatic biliary strictures. Our aim was to study the uselfulness of EUS-FNA in diagnosing CCA as the etiology of biliary strictures. PATIENTS AND METHODS In this meta-analysis,...

IEEE 802.15.4 LR-WPAN is a specification for low-cost, lowpowered and low data rate transmission. This standard uses CSMA/CA protocol for contention resolution. One of the tasks performed by CSMA/CA algorithm is Clear Channel Assessment (CCA), used to find the status (IDLE or BUSY) of the channel. There are three operating modes to perform CCA. As per the standard CCA mode 2 and 3 are based on ...

BACKGROUND Although many studies have confirmed a relationship between microRNAs (miRNAs) and cholangiocarcinoma (CCA), the real-time dynamics of miRNA function have not been examined. METHODS miRNA reporter constructs were generated using a recombinant adeno-associated virus vector, which contained complementary sequences for six miRNAs (miR-200a, miR-200b, miR-21, miR-146a, miR-155, and miR...

Cholangiocarcinoma (CCA) is a fatal cancer with poor prognosis and less than 10% of CCA patients can be offered surgical cure. Conventional chemotherapy results in unfavorable outcomes. At present, plant-derived compounds are gaining interest as potential cancer therapeutics, particularly for treatment-refractory cancers. In this study, antitumor activity of tiliacorinine, the major alkaloid is...

Cholangiocarcinoma (CCA) is the most common cancer in northeastern Thailand. At present, effective diagnosis of CCA either in humans or animals is not available. Monitoring the development and progression of CCA in animal models is essential for research and development of new promising chemotherapeutics. Ultrasonography has been widely used for screening of bile duct obstruction in CCA patient...