Pleasant cool and unpleasant cold sensations are thought to be mediated by distinct groups of peripheral thermoreceptor neurons that start spiking at different temperatures. The cold-sensitive transient receptor potential channel TRPM8 is present in these neurons, but if and how this channel alone can produce disparate thermal thresholds is not clear. This week, Madrid et al. suggest that slowl...

The motivation for this multi-part series is solely my observation that much of the writing on complexity theory seems to have arbitrarily ignored the vast systems theory literature. I don’t know whether this omission is deliberate (i.e., motivated by the political need to differentiate and promote one set of topical boundaries from another; a situation unfortunately driven by a reductionist fu...

Background: As Pandemic (H1N1) 2009 influenza spreads around the globe, it strikes school-age children more often than adults. Although there is some evidence of pre-existing immunity among older adults, this alone may not explain the significant gap in age-specific infection rates. Methods & Findings: Based on a retrospective analysis of pandemic strains of influenza from the last century, we ...

December 30, 1999 · Research Article Russ Marion, Josh Bacon, Dr Kurt Richardson1 1 Emergent Publications Marion R, Bacon J, Richardson K. Organizational Extinction and Complex Systems. Emergence: Complexity and Organization. 1999 Dec 30 [last modified: 2014 Nov 15]. Edition 1. The Lost World, Michael Crichton’s sequel to the dinosaur adventure Jurassic Park, is structured around complexity the...

(a) A courageous OP refers a boy aged eight who has †̃¿ gone off his legs' that morning. The OP says he knows it is hysterical but that he cannot stop it. The boy is brought by car. A kind psychiatrist negotiates through the window the need for the boy to mount the steps to come and talk. The boy comes. He talks about how his estranged father had promised first a trip to the cup final and then...

This paper is concerned with the problem of channel estimation for asynchronous DS-CDMA systems in the presence of local scattering of the multipaths. Based on a first order Taylor series expansion, the manifold vector associated with a locally scattered multipath is formulated and a new channel estimation algorithm is proposed. The proposed algorithm hinges on the patioemporal ray (STAR) manif...

mmPEEP, cm H2OPaw, cm H20Sa05, %Heart rate, beats/mmPressure,mm HgPa02, mm HgPaCO2, mm HgpHHCO3, mEq/LSo2, %[email protected](7810156886113146/7656387.3320851510559111114&752054892112150/75300459411515517682367.352996 confusing and improper, since PEEP in these settings not only increases the effect of shunting but also increases the dead space of a preexisting mismatch; ...

That is, the class JSf(A) of lattices representable by A-modules is the "quasivariety" of lattices satisfying J(A), for commutative A. OUTLINE OF PROOF. For A commutative, let i : L > r ( M ; A ) be an embedding for some M. Without loss of generality, assume that L has a smallest element co, and i{œ) = 0. Motivated by the "abelian" lattice Tf{G ) of [2,4.2] with G = M, we consider "constraint s...

The various soluble liver protein-carcinogen conjugates produced in vivo by two hepatocarcinogens have been resolved and analyzed according to molecular size. In addition, the molecular sizes of the principal soluble conjugates of three types of carcinogens have been compared in order to deduce whether they originate from a common or similar target pro tein. Adult male rats were fed the liver c...

This paper investigates the organization of the vowel space in French speakers. Speakers from 4 years of age to adulthood were recorded in order to generate significant betweenspeaker variability. Each speaker produced repetitions of the ten French oral vowels /i y u e ø o  œ  a/. Acoustic analyses show that despite considerable between-speaker variability in the relative positions of the vow...