In recent years, the level of heavy metal pollution in urban areas has been of considerable concern. The principal source has been attributed to the motor vehicle and increasing inner city congestion, which has lead to a change and enlargement of transport stop-start zones. These areas of high traffic density are associated with an increased release of heavy metals into the adjacent residential...

Constraining the timing of eukaryogenesis and divergence eukaryotic clades is a major challenge in evolutionary biology. Here, we present trace metal concentration zinc isotope data for c. 2.1 billion-year-old Francevillian Group pyritized structures, previously described as putative remnants first colonial multicellular organisms, their host black shales. Relative to rocks, structures are stro...

BACKGROUND Non-histone protein acylation is increasingly recognized as an important posttranslational modification, but little is known as to the biochemical properties of protein serine acylating enzymes. METHODOLOGY/PRINCIPAL FINDINGS We here report that we have identified a metal-stimulated serine octanoyltransferase activity in microsomes from human erythroleukemic (HEL) cells. The HEL ac...

Historically it has been shown repeatedly that single high doses of radiation do not allow a therapeutic differential between tumor and critical normal tissues but dose fractionation does. The purpose of conventional dose fractionation is to increase dose to the tumor while preserving normal tissue function. Tumors are generally irradiated with 2Gy dose per fraction delivered daily to a more or...

Distribution of pituitary gonadotropic activity among fractions of human postmenopausal plasma has been previously reported by the authors (I-3). When the plasma was separated into five fractions by the ethanol Method 6 of Cohn et al. (4), gonadotropic activity was found in Fraction II + III, although the other fractions were devoid of significant activity. The object of this communication is t...

Yeast aldolase was purified partially by Warburg and Christian (I), who found that it was inhibited by metal-binding agents and could be reactivated by addition of Fe++, Co++, or Zn++ ions. Later, this enzyme was further purified, treated with a chelating agent, and crystallized as a mercury salt (2). In this form, the enzyme was still active when tested in the presence of cysteine and Zn++ ion...

This research describes the use of a toxicity assay for the identification of metal toxicity, bioavailability and heavy metal binding capacity (HMBC) of municipal solid waste (MSW) landfill leachates. MetPLATE, an assay specific for heavy metal toxicity, was used to determine the HMBC of MSW leachates collected from 14 sites in Florida, with a wide range of chemical and physical characteristics...