A group has homological dimension ≤ 1 if it is locally free. We prove the converse provided that G satisfies the Atiyah Conjecture about L -Betti numbers. We also show that a finitely generated elementary amenable group G of cohomological dimension ≤ 2 possesses a finite 2dimensional model for BG and in particular that G is finitely presented and the trivial ZG-module Z has a 2-dimensional reso...

LIEBOW, C., AND S. S. ROTHMAN. Transport of bovine chymotrypsinogen into rabbit pancreatic cells. Am. J. Physiol. 226(5) : 1077-1081. 1974.-Chymotrypsinogen uptake was measured into slices of rabbit pancreas incubated in bovine chymotrypsinogen-3H and albumin J311. Chymotrypsinogen uptake was 16 times greater than that for albumin. Chymotrypsinogen-3H was not readily “chased” by washing in cold...

The computation of the projective surgery obstruction groups LP.(ZG), for G a hyperelementary finite group, is reduced to standard calculations in number theory, mostly involving class groups. Both the exponent of the torsion subgroup and the precise divisibility of the signatures are determined. For G a 2-hyperelementary group, the LP.(ZG) are detected by restriction to certain subquotients of...

In pancreatic acinar cells Ca(2+)-dependent secretagogues promote the fusion of zymogen granules (ZG) with the apical plasma membrane (PM) and exocytosis of digestive enzymes. In addition to exocytotic fusion complexes between SNARE proteins in the ZG membrane (ZGM) and the apical PM, enzyme secretion elicited by Ca(2+)-dependent secretagogues requires cytosolic Cl and K+ and is inhibited by bl...

Background We examined the effect of antioxidant supplementation and exercise on irisin within postmenopausal women. Methods Forty-eight participants (age: 55.7 ± 4.9 years; weight: 68.0 ± 6.3 kg; BMI 27.0 ± 2.7; mean ± SD) were randomized into four groups for the eight week intervention: control group (CG; n = 12), resistance training group (RTG; n = 12), supplementation with Zataria multifl...

The regulation of aldosterone synthesis by endogenous nitric oxide (NO) was examined in cultured cells of the adrenal cortex. Endothelial NO synthase (eNOS) was detected by Western blot in cultured adrenal endothelial cells (ECs) but not in zona glomerulosa (ZG) cells or adrenal fibroblasts. Neither inducible (iNOS) nor neuronal NOS (nNOS) isoforms were detected in the cells. Only ECs had NOS a...

Zymogen granule (ZG) formation in acinar cells involves zymogen cargo sorting from trans-Golgi into immature secretory granules (ISGs). ISG maturation progresses by removal of lysosomal membrane and select content proteins, which enter endosomal intermediates prior to their apical exocytosis. Constitutive and stimulated secretion through this mechanism is termed the constitutive-like and minor-...

Two vectors x, y in Zg are qualitatively independent if for all pairs (a, b) ∈ Zg×Zg, there exists i ∈ {1, 2, . . . , n} such that (xi, yi) = (a, b). A covering array on a graph G, denoted by CA(n,G, g), is a |V (G)|×n array on Zg with the property that any two rows which correspond to adjacent vertices in G are qualitatively independent. The number of columns in such array is called its size. ...