Dr Backer is a consultant for W. L. Gore & Associates, Inc.The Journal policy requires editors and reviewers to disclose conflicts of interest decline handling or reviewing manuscripts which they may have conflict interest. The this article no Inc. I greatly appreciate the comments Vervoort,1Vervoort D. Centralization regionalization congenital heart surgery in globalized world.J Thorac Cardiov...

EMBL-EBI’s Protein Data Bank in Europe [2] (PDBe) is the European resource for the collection, organisation and dissemination of data about biological macromolecular structures. PDBe is one of four partners in the Worldwide Protein Data Bank [3] (wwPDB, see information box below), the consortium entrusted with the collation, maintenance and distribution of the single global repository of macrom...

Scientists in all domains face a data avalanche both from better instruments and from improved simulations. We believe that computer science tools and computer scientists are in a position to help all the sciences by building tools and developing techniques to manage, analyze, and visualize peta-scale scientific information. This article summarizes our experiences over the last seven years tryi...